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D.A. Leonard
D.A. Leonard
University of Virginia
Biochemistry
Lanosterol
Biology
Reductase
Demethylase
4
Papers
113
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15-Substituted Lanosterols: Post-transcriptional Suppressors of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase
1995
Archives of Biochemistry and Biophysics
J.A. Anderson
D.A. Leonard
K.P. Cusack
L.L. Frye
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Citations (11)
Post-transcriptional Regulation of 3-Hydroxy-3-methylglutaryl Coenzyme-A Reductase by 3β-Hydroxy-Lanost-8-en-32-Al, an Intermediate in the Conversion of Lanosterol to Cholesterol
1994
Archives of Biochemistry and Biophysics
D.A. Leonard
M.A. Kotarski
J.E. Tessiatore
M.F. Favata
J.M. Trzaskos
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Citations (27)
Modulation of 3-hydroxy-3-methylglutaryl-CoA reductase by 15 alpha-fluorolanost-7-en-3 beta-ol. A mechanism-based inhibitor of cholesterol biosynthesis.
1993
Journal of Biological Chemistry
James M. Trzaskos
Ronald L. Magolda
Margaret F. Favata
R T Fischer
Paul R. Johnson
H.W Chen
Soo S. Ko
D.A. Leonard
James L. Gaylor
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Citations (44)
A mammalian mutant cell lacking detectable lanosterol 14 alpha-methyl demethylase activity.
1988
Journal of Biological Chemistry
H.W Chen
D.A. Leonard
R T Fischer
James M. Trzaskos
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Citations (31)
1