Lanosterol

Lanosterol is a tetracyclic triterpenoid and is the compound from which all animal and fungal steroids are derived. By contrast plant steroids are produced via cycloartenol. Lanosterol is a tetracyclic triterpenoid and is the compound from which all animal and fungal steroids are derived. By contrast plant steroids are produced via cycloartenol. Researchers who have pioneered the use of lanosterol in eyedrop form — to treat or prevent cataracts — include Kang Zhang and Ling Zhao. Elaboration of lanosterol under enzyme catalysis leads to the core structure of steroids. 14-Demethylation of lanosterol by CYP51 eventually yields cholesterol. Recent research suggests that lanosterol might be instrumental in prevention of formation of cataracts in mammals. While there are some claims of it also reducing existing cataracts, primarily when they are cortical (on the surface of the lens), some studies have failed to produce results more significant than placebo.