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Yoshiaki Oyama

Gunma University

32

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518

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Design, synthesis, and biological evaluation of spiroindolines as novel inducers of oligodendrocyte progenitor cell differentiation—Use of a conformation-based hypothesis to facilitate compound design

2020 Bioorganic & Medicinal Chemistry Letters
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Benzothiophene derivatives as phosphodiesterase 10A (PDE10A) inhibitors: Hit-to-lead studies

2019 Bioorganic & Medicinal Chemistry Letters
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Structure-based drug design to overcome species differences in kallikrein 7 inhibition of 1,3,6-trisubstituted 1,4-diazepan-7-ones.

2018 Bioorganic & Medicinal Chemistry
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Structure-based drug design of 1,3,6-trisubstituted 1,4-diazepan-7-ones as selective human kallikrein 7 inhibitors

2018 Bioorganic & Medicinal Chemistry Letters
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Discovery and in vivo effects of novel human natriuretic peptide receptor A (NPR-A) agonists with improved activity for rat NPR-A

2017 Bioorganic & Medicinal Chemistry
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Discovery and SAR of a novel series of Natriuretic Peptide Receptor-A (NPR-A) agonists

2017 Bioorganic & Medicinal Chemistry Letters
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Notch signaling regulates the differentiation of bone marrow-derived cells into smooth muscle-like cells during arterial lesion formation.

2009 Biochemical and Biophysical Research Communications
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Direct Interaction of Multidrug Efflux Transporter AcrB and Outer Membrane Channel TolC Detected via Site-Directed Disulfide Cross-Linking†

2005 Biochemistry
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Structural Models of the Photointermediates in the Rhodopsin Photocascade, Lumirhodopsin, Metarhodopsin I, and Metarhodopsin II

2004 ChemBioChem
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pKa measurements from nuclear magnetic resonance of tyrosine-150 in class C beta-lactamase.

2003 Biochemical Journal
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Citations (37)