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Marianne Kjalke

Novo Nordisk

51

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Thrombin generation potential in the presence of concizumab and rFVIIa, aPCC, rFVIII or rFIX: In vitro and ex vivo analyses.

2021 Journal of Thrombosis and Haemostasis
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The in Vitro Effect on Thrombin Generation of Adding rFVIII or rFIX to Hemophilia a or b Plasma in the Absence or Presence of Concizumab

2020 Blood
- Marianne Kjalke
- Søren Andersen
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A Novel Next-Generation FVIII Mimetic, Mim8, Has a Favourable Safety Profile. Results from a 26-Week Safety Study in Cynomolgus Monkeys

2020 Blood
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An overview of turoctocog alfa pegol (N8-GP; ESPEROCT® ) assay performance: Implications for postadministration monitoring

2019 Haemophilia
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Thrombin Generation Assay in Plasma from Hemophilia a Patients with or without Inhibitors on Concizumab Prophylaxis: Spiking with rFVIIa or aPCC

2019 Blood
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Factor VIII with a 237 amino acid B‐domain has an extended half‐life in F8‐knockout mice

2019 Journal of Thrombosis and Haemostasis
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Preclinical pharmacokinetics and biodistribution of subcutaneously administered glycoPEGylated recombinant factor VIII (N8‐GP) and development of a human pharmacokinetic prediction model

2018 Journal of Thrombosis and Haemostasis
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Factor VIII chromogenic assays can be used for potency labeling and postadministration monitoring of N8-GP.

2016 Journal of Thrombosis and Haemostasis
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efficacy and prolonged effect in hemophilic mice models A novel B-domain O-glycoPEGylated FVIII (N8-GP) demonstrates full

2013
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Faktor-VIII-Moleküle mit reduzierter VWF-Bindung

2011
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