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Lihua Chen
Lihua Chen
Bristol-Myers Squibb
Enzyme
Biochemistry
Chemistry
Chemical synthesis
Hydroxamic acid
3
Papers
173
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Discovery of β-benzamido hydroxamic acids as potent, selective, and orally bioavailable TACE inhibitors
2008
Bioorganic & Medicinal Chemistry Letters
James J.-W. Duan
Lihua Chen
Zhonghui Lu
Chu Biao Xue
Rui-Qin Liu
Maryanne Covington
Mingxin Qian
Zelda R. Wasserman
Krishna Vaddi
David D. Christ
James M. Trzaskos
Robert C. Newton
Carl P. Decicco
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Citations (23)
Discovery of low nanomolar non-hydroxamate inhibitors of tumor necrosis factor-α converting enzyme (TACE)
2007
Bioorganic & Medicinal Chemistry Letters
James J.-W. Duan
Lihua Chen
Zhonghui Lu
Bin Jiang
Naoyuki Asakawa
James E. Sheppeck
Rui-Qin Liu
Maryanne B. Covington
William J. Pitts
Soong-Hoon Kim
Carl P. Decicco
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Citations (37)
Discovery of γ-Lactam Hydroxamic Acids as Selective Inhibitors of Tumor Necrosis Factor α Converting Enzyme: Design, Synthesis, and Structure−Activity Relationships
2002
Journal of Medicinal Chemistry
James J.-W. Duan
Lihua Chen
Zelda R. Wasserman
Zhonghui Lu
Rui-Qin Liu
Maryanne Covington
Mingxin Qian
Karl D. Hardman
Ronald L. Magolda
Robert Newton
David D. Christ
Ruth R. Wexler
Carl P. Decicco
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Citations (113)
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