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Josh Yuan

Takeda Pharmaceutical Company

6

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A reduction in B, T, and NK cells expressing CD38 by TAK-079 inhibits the induction and progression of collagen-induced arthritis in cynomolgus monkeys

2019 Journal of Pharmacology and Experimental Therapeutics
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A Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the “Metabolites in Safety Testing” Regulatory Guidance

2018 Drug Metabolism and Disposition
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TAK-079 is a high affinity monoclonal antibody that effectively mediates CD38+ cell depletion

2017 Journal of Immunology
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Pharmacokinetics and metabolism of a COX-2 inhibitor, valdecoxib, in mice

2003 Drug Metabolism and Disposition
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Disposition of a specific cyclooxygenase-2 inhibitor, valdecoxib, in human

2002 Drug Metabolism and Disposition
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