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Lixia Jin

United States Military Academy

20

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Synthesis of 5-(1-H or 1-alkyl-5-oxopyrrolidin-3-yl)-8-hydroxy-[1,6]-naphthyridine-7-carboxamide inhibitors of HIV-1 integrase

2008 Bioorganic & Medicinal Chemistry Letters
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with oral administration of a BACE1 inhibitor in nonhuman primates

2008
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A potent and orally active HIV-1 integrase inhibitor.

2007 Bioorganic & Medicinal Chemistry Letters
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Gene expression profiling of rat liver reveals a mechanistic basis for ritonavir-induced hyperlipidemia

2007 Genomics
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BACE-1 inhibition by a series of ψ[CH2NH] reduced amide isosteres

2006 Bioorganic & Medicinal Chemistry Letters
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A series of 5-aminosubstituted 4-fluorobenzyl-8-hydroxy-[1,6]naphthyridine-7-carboxamide HIV-1 integrase inhibitors

2006 Bioorganic & Medicinal Chemistry Letters
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Orally bioavailable highly potent HIV protease inhibitors against PI-resistant virus.

2005 Bioorganic & Medicinal Chemistry Letters
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A series of 5-(5,6)-dihydrouracil substituted 8-hydroxy-[1,6]naphthyridine-7-carboxylic acid 4-fluorobenzylamide inhibitors of HIV-1 integrase and viral replication in cells

2005 Bioorganic & Medicinal Chemistry Letters
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Integrase Inhibitors and Cellular Immunity Suppress Retroviral Replication in Rhesus Macaques

2004 Science
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Novel HIV-1 protease inhibitors active against multiple PI-Resistant viral strains: coadministration with indinavir

2003 Bioorganic & Medicinal Chemistry Letters
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