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Natacha Stoehr

Novartis

13

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2145

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Atg4b-dependent autophagic flux alleviates Huntington's disease progression.

2013 PLOS ONE
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Citations (27)
A selective metabotropic glutamate receptor 7 agonist: Activation of receptor signaling via an allosteric site modulates stress parameters in vivo

2005 Proceedings of the National Academy of Sciences of the United States of America
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(-)-PHCCC, a positive allosteric modulator of mGluR4: characterization, mechanism of action, and neuroprotection

2003 Neuropharmacology
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[3H]-M-MPEP, a Potent, Subtype-Selective Radioligand for the Metabotropic Glutamate Receptor Subtype 5

2002 Bioorganic & Medicinal Chemistry Letters
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Discovery and characterization of non-competitive antagonists of group I metabotropic glutamate receptors

2001 Farmaco
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Metabotropic glutamate receptor subtype 5 (mGlu5) and nociceptive function I. Selective blockade of mGlu5 receptors in models of acute, persistent and chronic pain

2001 Neuropharmacology
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Metabotropic glutamate receptor subtype 5 (mGlu5) and nociceptive function

2001 Neuropharmacology
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The non-competitive antagonists 2-methyl-6-(phenylethynyl)pyridine and 7-hydroxyiminocyclopropan[b]chromen-1a-carboxylic acid ethyl ester interact with overlapping binding pockets in the transmembrane region of group I metabotropic glutamate receptors.

2000 Journal of Biological Chemistry
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2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist.

1999 Neuropharmacology
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CPCCOEt, a noncompetitive metabotropic glutamate receptor 1 antagonist, inhibits receptor signaling without affecting glutamate binding.

1999 Molecular Pharmacology
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Citations (315)