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Micheline Heinrich

Novartis

10

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1399

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[3H]-M-MPEP, a Potent, Subtype-Selective Radioligand for the Metabotropic Glutamate Receptor Subtype 5

2002 Bioorganic & Medicinal Chemistry Letters
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Discovery and characterization of non-competitive antagonists of group I metabotropic glutamate receptors

2001 Farmaco
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Radiolabelling and in vivo evaluation of 11C–MPEP as a pet radioligand for the imaging of the metabotropic glutamate receptor 5 (MGLUR5)

2001 Journal of Labelled Compounds and Radiopharmaceuticals
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The non-competitive antagonists 2-methyl-6-(phenylethynyl)pyridine and 7-hydroxyiminocyclopropan[b]chromen-1a-carboxylic acid ethyl ester interact with overlapping binding pockets in the transmembrane region of group I metabotropic glutamate receptors.

2000 Journal of Biological Chemistry
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2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist.

1999 Neuropharmacology
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Effects of selective dopamine D1 and D2 receptor agonists on the rate of GABA synthesis in mouse brain

1990 European Journal of Pharmacology
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Interaction of the D1 Receptor Antagonist Sch 23390 with the Central 5-HT System: Radioligang Binding Studies, Measurements of Biochemical Parameters and Effects on L-5-HTP Syndrome

1988 Journal of Receptors and Signal Transduction
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The D-1 dopamine receptor antagonist SCH 23390 also interacts potently with brain serotonin (5-HT2) receptors

1986 European Journal of Pharmacology
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Discrimination of neuroleptics by means of their interaction with amfonelic acid: An attempt to characterize the test

1985 Biochemical Pharmacology
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Citations (13)