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Thomas S. Dexheimer

Michigan State University

18

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177

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The AKT modulator A-443654 reduces α-synuclein expression and normalizes ER stress and autophagy.

2021 Journal of Biological Chemistry
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Reversal of Infected Host Gene Expression Identifies Repurposed Drug Candidates for COVID-19

2020 bioRxiv
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Hyperphosphorylated tau aggregation and cytotoxicity modulators screen identified prescription drugs linked to Alzheimer's disease and cognitive functions.

2020 Scientific Reports
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Two highly related odorant receptors specifically detect α-bile acid pheromones in sea lamprey (Petromyzon marinus).

2020 Journal of Biological Chemistry
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5-Aryl-1,3,4-oxadiazol-2-ylthioalkanoic Acids: A Highly Potent New Class of Inhibitors of Rho/Myocardin-Related Transcription Factor (MRTF)/Serum Response Factor (SRF)-Mediated Gene Transcription as Potential Antifibrotic Agents for Scleroderma

2019 Journal of Medicinal Chemistry
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Abstract C063: A novel Nrf2 inhibitor suppresses proliferation and enhances the sensitivity of cancer cells to chemotherapy

2019 Molecular Cancer Therapeutics
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Spermine in semen of male sea lamprey acts as a sex pheromone

2019 PLOS Biology
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Inhibition of the Myocardin-Related Transcription Factor pathway increases efficacy of Trametinib in NRAS-mutant melanoma cell lines

2019 bioRxiv
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Abstract 1: A small molecule inhibits Nrf2 expression and activity in cancer cells

2019 Cancer Research
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Identification of Pirin as a Molecular Target of the CCG-1423/CCG-203971 Series of Antifibrotic and Antimetastatic Compounds

2019 bioRxiv
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