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Charles J. Guinosso

Isis Pharmaceuticals

29

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1785

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Oligonucleotide Transport Across Membranes and Into Cells: Effects of Chemical Modifications

2017
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Solution Phase Combinatorial Chemistry. Synthesis of Novel Linear Pyridinopolyamine Libraries with Potent Antibacterial Activity.

2010 ChemInform
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Pharmacokinetic properties of several novel oligonucleotide analogs in mice.

1996 Journal of Pharmacology and Experimental Therapeutics
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2'-O-Aminopropyl ribonucleotides : A zwitterionic modification that enhances the exonuclease resistance and biological activity of antisense oligonucleotides

1996 Journal of Medicinal Chemistry
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Drug leads from combinatorial phosphodiester libraries

1995 Journal of Medicinal Chemistry
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Characterization of fully 2'-modified oligoribonucleotide hetero- and homoduplex hybridization and nuclease sensitivity.

1995 Nucleic Acids Research
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Acyclic nucleoside analogues and oligonucleotide sequences containing these

1994
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Acyclic nucleoside analog containing them oligonucleotide

1994
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Lipid membrane permeability of 2′‐modified derivatives of phosphorothioate oligonucleotides

1994 Journal of Pharmaceutical Sciences
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Oligodeoxynucleotides containing 2'-O-modified adenosine: Synthesis and effects on stability of DNA:RNA duplexes

1993 Biochemistry
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Citations (186)