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Xiaoming Wen

Incyte

20

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1000

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A Potent and Selective Dual Inhibitor of AXL and MERTK Possesses Both Immunomodulatory and Tumor-Targeted Activity

2020 Frontiers in Oncology
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The Novel Bromodomain and Extraterminal Domain Inhibitor INCB054329 Induces Vulnerabilities in Myeloma Cells That Inform Rational Combination Strategies

2019 Clinical Cancer Research
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Abstract 1876: INCB052793, a JAK1 selective inhibitor, is highly efficacious in PDX and xenograft models of acute myeloid leukemia (AML) expressing elevated endogenous pSTAT3/pSTAT5

2018 Cancer Research
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Abstract 1234: The novel FGFR4-selective inhibitor INCB062079 is efficacious in models of hepatocellular carcinoma harboring FGF19 amplification

2017 Cancer Research
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Abstract 5071: Preclinical characterization of the potent and selective BET inhibitor INCB057643 in models of hematologic malignancies

2017 Cancer Research
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Abstract 2032: Combination of epigenetic regulation via LSD1 inhibition with signal transduction inhibitors significantly enhances anti-tumor activity in models of hematologic malignancies

2017 Cancer Research
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Abstract 692: The BET inhibitor INCB054329 is synergistic with JAK1 inhibition in models of multiple myeloma

2015 Cancer Research
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Abstract 3523: Discovery of a novel BET inhibitor INCB054329

2015 Cancer Research
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Abstract 3525: The BET inhibitor INCB054329 is efficacious as a single agent or in combination with targeted agents in colorectal cancer models

2015 Cancer Research
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Abstract 5414: Activity of the pan-PIM kinase inhibitor INCB053914 in models of multiple myeloma

2015 Cancer Research
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