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Jeffrey D. Parvin

Ohio State University
Brigham and Women's Hospital

140

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Modulation of Early Mitotic Inhibitor 1 (EMI1) Depletion on the Sensitivity of PARP Inhibitors in BRCA1 Mutated Triple-Negative Breast Cancer Cells

2020 bioRxiv
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Abstract 4093: Drug combinations that can overcome resistance to PARP inhibitor therapy for BRCA1-associated breast cancer

2020
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Functional analysis of BARD1 missense variants in homology-directed repair and damage sensitivity

2019 PLOS Genetics
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F-Box Protein-Mediated Resistance to PARP Inhibitor Therapy

2019 Molecular Cell
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Characterizing BRCA1 Variants Using Multiplex Functional Assays

2019
- Aleksandra I. Adamovich
- Jeffrey D. Parvin
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Abstract 1285: Deep mutagenesis analysis onBRCA1variants in high throughput DNA repair assays

2018 Cancer Research
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Abstract 1367: BRCA1 and BARD1 protein interactions that are required for DNA repair function

2018 Cancer Research
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A multiplexed homology-directed DNA repair assay reveals the impact of ~1,700 BRCA1 variants on protein function

2018 bioRxiv
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A Multiplex Homology-Directed DNA Repair Assay Reveals the Impact of More Than 1,000 BRCA1 Missense Substitution Variants on Protein Function

2018 American Journal of Human Genetics
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Camptothecin resistance is determined by the regulation of topoisomerase I degradation mediated by ubiquitin proteasome pathway

2017 Oncotarget
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