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Daigen Xu
Daigen Xu
Washington University in St. Louis
Biochemistry
Prostaglandin
Inflammation
Chemistry
Caspase 3
4
Papers
311
Citations
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The discovery of 4-{1-[({2,5-dimethyl-4-[4-(trifluoromethyl)benzyl]-3-thienyl}carbonyl)amino]cyclopropyl}benzoic acid (MK-2894), a potent and selective prostaglandin E2 subtype 4 receptor antagonist.
2010
Journal of Medicinal Chemistry
Marc Blouin
Yongxin Han
Jason Burch
Julie Farand
Christophe Mellon
Mireille Gaudreault
Mark Wrona
Jean François Lévesque
Danielle Denis
Marie-Claude Mathieu
Rino Stocco
Erika Vigneault
Alex G. Therien
Patsy Clark
Steve Rowland
Daigen Xu
Gary P. O'Neill
Yves Ducharme
Rick Friesen
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Citations (21)
MF63 [2-(6-Chloro-1H-phenanthro[9,10-d]imidazol-2-yl)-isophthalonitrile], a Selective Microsomal Prostaglandin E Synthase-1 Inhibitor, Relieves Pyresis and Pain in Preclinical Models of Inflammation
2008
Journal of Pharmacology and Experimental Therapeutics
Daigen Xu
Steven E. Rowland
Patsy Clark
André Giroux
Bernard Cote
Sébastien Guiral
Myriam Salem
Yves Ducharme
Richard Friesen
Nathalie Méthot
Joseph A. Mancini
Laurent Audoly
Denis Riendeau
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Citations (133)
Procédés permettant de traiter ou de prévenir des néoplasies
2007
Stacia Kargman
Gary P. O'Neill
Daigen Xu
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Selective, reversible caspase-3 inhibitor is neuroprotective and reveals distinct pathways of cell death after neonatal hypoxic-ischemic brain injury
2002
Journal of Biological Chemistry
Byung-Hee Han
Daigen Xu
Junjeong Choi
Yongxin Han
Steven Xanthoudakis
Sophie Roy
John Tam
John Vaillancourt
John Colucci
Robert Siman
Andre Giroux
George S. Robertson
Robert Zamboni
Donald W. Nicholson
David M. Holtzman
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Citations (157)
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