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Georgianna Harris

Merck & Co.

46

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Discovery of betamethasone 17α-carbamates as dissociated glucocorticoid receptor modulators in the rat

2008 Bioorganic & Medicinal Chemistry
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Novel glucocorticoids containing a 6,5-bicyclic core fused to a pyrazole ring: synthesis, in vitro profile, molecular modeling studies, and in vivo experiments.

2007 Bioorganic & Medicinal Chemistry Letters
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The discovery of moriniafungin, a novel sordarin derivative produced by Morinia pestalozzioides

2006 Bioorganic & Medicinal Chemistry
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Novel heterocyclic glucocorticoids: in vitro profile and in vivo efficacy.

2005 Bioorganic & Medicinal Chemistry Letters
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Selective glucocorticoid receptor nonsteroidal ligands completely antagonize the dexamethasone mediated induction of enzymes involved in gluconeogenesis and glutamine metabolism.

2004 The Journal of Steroid Biochemistry and Molecular Biology
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Novel N-arylpyrazolo [3,2-c]-based ligands for the glucocorticoid receptor : receptor binding and in vivo activity

2004 Journal of Medicinal Chemistry
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Glucose-Lowering in a db/db Mouse Model by Dihydropyridine Diacid Glycogen Phosphorylase Inhibitors.

2004 ChemInform
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Novel 3,4-Dihydroquinolin-2(1H)-one Inhibitors of Human Glycogen Phosphorylase a.

2004 ChemInform
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Skeletal muscle: a dual system to measure glucocorticoid-dependent transactivation and transrepression of gene regulation

2004 The Journal of Steroid Biochemistry and Molecular Biology
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Novel pyrazolo[3,4-d]pyrimidine-based inhibitors of Staphlococcus aureus DNA polymerase III: design, synthesis, and biological evaluation.

2003 Journal of Medicinal Chemistry
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