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Mark Wappett

AstraZeneca

20

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351

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classifieR a flexible interactive cloud-application for functional annotation of cancer transcriptomes.

2022 BMC Bioinform.
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Abstract LB096: Development of a next generation ROR1 targeting Protein Drug Conjugate (PDC)

2021 Cancer Research
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Abstract 538: Exploiting the properties of VNAR domains for the development of novel efficacious protein drug conjugates targeting the oncofetal protein ROR1

2020 Cancer Research
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Abstract 222: Novel protein drug conjugates targeting ROR1 through the development and exploitation of a drug discovery platform based on small, engineered VNAR domains

2019 Cancer Research
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Abstract LB-087: Discovery and development of first-in-class orally bioavailable USP19 inhibitors

2019 Cancer Research
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Abstract 1935: Accessing the cancer DUBome with UbiPlex: A bespoke drug discovery platform for deubiquitinase enzymes

2018 Cancer Research
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Leptin, BMI, and a Metabolic Gene Expression Signature Associated with Clinical Outcome to VEGF Inhibition in Colorectal Cancer.

2016 Cell Metabolism
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Enhanced MAPK signaling drives ETS1-mediated induction of miR-29b leading to downregulation of TET1 and changes in epigenetic modifications in a subset of lung SCC

2016 Oncogene
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Reproducible, Quantitative, and Flexible Molecular Subtyping of Clinical DLBCL Samples Using the NanoString nCounter System.

2015 Clinical Cancer Research
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Abstract 4171: Integrating pan-molecular data sets by bimodality to nominate synthetic lethal gene pairs and biomarkers of drug response

2014 Cancer Research
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