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Tomohiro Nakamura

Sanford-Burnham Institute for Medical Research
Scripps Research Institute

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S-nitrosylated TDP-43 triggers aggregation, cell-to-cell spread, and neurotoxicity in hiPSCs and in vivo models of ALS/FTD.

2021 Proceedings of the National Academy of Sciences of the United States of America
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TCA cycle metabolic compromise due to an aberrant S-nitrosoproteome in HIV-associated neurocognitive disorder with methamphetamine use.

2021 Journal of NeuroVirology
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Protein S-nitrosylation and oxidation contribute to protein misfolding in neurodegeneration.

2021 Free Radical Biology and Medicine
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Protein Transnitrosylation Signaling Networks Contribute to Inflammaging and Neurodegenerative Disorders

2021 Antioxidants & Redox Signaling
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Control of mammalian brain aging by the unfolded protein response (UPR)

2020 bioRxiv
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NitroSynapsin ameliorates hypersynchronous neural network activity in Alzheimer hiPSC models.

2020 Molecular Psychiatry
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Noncanonical transnitrosylation network contributes to synapse loss in Alzheimer's disease.

2020 Science
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F1000Prime recommendation of Small-Molecule Modulation of TDP-43 Recruitment to Stress Granules Prevents Persistent TDP-43 Accumulation in ALS/FTD.

2020
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NitroSynapsin for the treatment of neurological manifestations of tuberous sclerosis complex in a rodent model

2019 Neurobiology of Disease
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Nitric Oxide-Dependent Protein Posttranslational Modifications Impair Mitochondrial Function and Metabolism to Contribute to Neurodegenerative Diseases

2019 Antioxidants & Redox Signaling
- Tomohiro Nakamura
- Stuart A. Lipton
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Citations (19)