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André Strauss

Novartis

36

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2553

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A simple protocol for amino acid type selective isotope labeling in insect cells with improved yields and high reproducibility

2011 Journal of Biomolecular NMR
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2,6-Naphthyridines as potent and selective inhibitors of the novel protein kinase C isozymes.

2011 Bioorganic & Medicinal Chemistry Letters
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Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery.

2010 Nature Chemical Biology
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Targeting Bcr–Abl by combining allosteric with ATP-binding-site inhibitors

2010 Nature
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Inhibitors of the Abl kinase directed at either the ATP- or myristate-binding site.

2010 Biochimica et Biophysica Acta
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Binding or bending: distinction of allosteric Abl kinase agonists from antagonists by an NMR-based conformational assay.

2010 Journal of the American Chemical Society
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Discovery of 3-(1H-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]pyrrole-2,5-dione (AEB071), a potent and selective inhibitor of protein kinase C isotypes

2009 Journal of Medicinal Chemistry
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NMR-Based Strategies to Elucidate Bioactive Conformations of Weakly Binding Ligands.

2008 Topics in Current Chemistry
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Recombinant hirustasin: Production in yeast, crystallization, and interaction with serine proteases

2008 Protein Science
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Backbone 1H, 15N, 13CO and 13CA resonance assignment of ABL kinase domain in complex with imatinib

2008 Journal of Back and Musculoskeletal Rehabilitation
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