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Stephan Grzesiek

University of Basel
National Institutes of Health

236

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38115

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Efficient production of a functional G protein-coupled receptor in E. coli for structural studies.

2021 Journal of Biomolecular NMR
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Filling of a water-free void explains the allosteric regulation of the β1-adrenergic receptor by cholesterol

2021 bioRxiv
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Structural and Biochemical Studies Confirming the Mechanism of Action of Asciminib, an Agent Specifically Targeting the ABL Myristoyl Pocket (STAMP)

2020 Blood
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Solution structure of protein ARR_CleD in complex with c-di-GMP

2020
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Structural basis of the activation of the CC chemokine receptor 5 by a chemokine agonist

2020 bioRxiv
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Intercepting second-messenger signaling by rationally designed peptides sequestering c-di-GMP.

2020 Proceedings of the National Academy of Sciences of the United States of America
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A high-resolution description of β1-adrenergic receptor functional dynamics and allosteric coupling from backbone NMR.

2020 Nature Communications
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Deuterium induces a distinctive Escherichia coli proteome that correlates with the reduction in growth rate

2019 Journal of Biological Chemistry
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High pressure shifts the β1-adrenergic receptor to the active conformation in the absence of G protein

2019 Journal of the American Chemical Society
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ATP Site Ligands Determine the Assembly State of the Abelson Kinase Regulatory Core via the Activation Loop Conformation

2018 Journal of the American Chemical Society
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