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Katalin Saghy

42

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Preclinical pharmacodynamic and pharmacokinetic characterization of the major metabolites of cariprazine

2019 Drug Design Development and Therapy
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Purkinje cell number-correlated cerebrocerebellar circuit anomaly in the valproate model of autism

2018 bioRxiv
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Discovery of 4-amino-3-arylsulfoquinolines, a novel non-acetylenic chemotype of metabotropic glutamate 5 (mGlu5) receptor negative allosteric modulators

2017 European Journal of Medicinal Chemistry
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Discovery and Preclinical Characterization of 3-((4-(4-Chlorophenyl)-7-fluoroquinoline-3-yl)sulfonyl)benzonitrile, a Novel Non-acetylenic Metabotropic Glutamate Receptor 5 (mGluR5) Negative Allosteric Modulator for Psychiatric Indications

2017 Journal of Medicinal Chemistry
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4-Aryl-3-arylsulfonyl-quinolines as negative allosteric modulators of metabotropic GluR5 receptors: From HTS hit to development candidate

2016 Bioorganic & Medicinal Chemistry Letters
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Poster #S17 ARE DOPAMINE PARTIAL AGONIST ANTIPSYCHOTICS SIMILAR? PRECLINICAL COMPARISON OF ARIPIPRAZOLE, BIFEPRUNOX AND CARIPRAZINE

2014 Schizophrenia Research
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Cariprazine (RGH-188), a D3-preferring dopamine D3/D2 receptor partial agonist antipsychotic candidate demonstrates anti-abuse potential in rats

2013 Psychopharmacology
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Discovery of cariprazine (RGH-188): A novel antipsychotic acting on dopamine D3/D2 receptors

2012 Bioorganic & Medicinal Chemistry Letters
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Effects of 5-HT6 antagonists, Ro-4368554 and SB-258585, in tests used for the detection of cognitive enhancement and antipsychotic-like activity.

2011 Behavioural Pharmacology
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THE PHARMACOLOGY OF CARIPRAZINE, A NOVEL D3-PREFERRING D3/D2 ANTAGONIST-PARTIAL AGONIST ANTIPSYCHOTIC

2010 Schizophrenia Research
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