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Amrita Bobok

12

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Discovery of 4-amino-3-arylsulfoquinolines, a novel non-acetylenic chemotype of metabotropic glutamate 5 (mGlu5) receptor negative allosteric modulators

2017 European Journal of Medicinal Chemistry
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Discovery and Preclinical Characterization of 3-((4-(4-Chlorophenyl)-7-fluoroquinoline-3-yl)sulfonyl)benzonitrile, a Novel Non-acetylenic Metabotropic Glutamate Receptor 5 (mGluR5) Negative Allosteric Modulator for Psychiatric Indications

2017 Journal of Medicinal Chemistry
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4-Aryl-3-arylsulfonyl-quinolines as negative allosteric modulators of metabotropic GluR5 receptors: From HTS hit to development candidate

2016 Bioorganic & Medicinal Chemistry Letters
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Cell-based and virtual fragment screening for adrenergic α2C receptor agonists.

2015 Bioorganic & Medicinal Chemistry
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Poster #16 CARIPRAZINE, A D3/D2 DOPAMINE RECEPTOR PARTIAL AGONIST ANTIPSYCHOTIC, DISPLAYS GREATER D3 RECEPTOR OCCUPANCY IN VIVO COMPARED WITH OTHER ANTIPSYCHOTICS

2012 Schizophrenia Research
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In vitro and in vivo comparison of [3H](+)-PHNO and [3H]raclopride binding to rat striatum and lobes 9 and 10 of the cerebellum: A method to distinguish dopamine D3 from D2 receptor sites: A method to distinguish dopamine D3 from D2 receptor sites

2011 Synapse
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Hit-to-lead optimization of disubstituted oxadiazoles and tetrazoles as mGluR5 NAMs

2010 Bioorganic & Medicinal Chemistry Letters
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Carbamoyloximes as novel non-competitive mGlu5 receptor antagonists

2010 Bioorganic & Medicinal Chemistry Letters
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Sulfonyl derivatives-quinoline

2008
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Derives de tetrazole utilises comme modulateurs de recepteurs metabotropiques du glutamate

2006
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