author-photo

Mandy Lawson

AstraZeneca

31

Papers

872

Citations

Citation Trend

Filter By

Papers (22) Sort By

Journal Conference Others

Abstract 5674: Discovery of AZD9833, an oral small molecule selective degrader of the estrogen receptor (SERD)

2020
Show All
- Source
- Cite
- Save
Citations (2)
Abstract 4379: Not all selective estrogen receptor degraders are equal - Preclinical comparison of AZD9833, AZD9496 and fulvestrant

2020 Epidemiology
Show All
- Source
- Cite
- Save
Citations (1)
Abstract P6-04-15: Oral selective estrogen receptor degrader AZD9496 demonstrated preclinical model specific differences to fulvestrant in estrogen receptor degradation, agonism and anti-tumour effects

2020 Cancer Research
Show All
- Source
- Cite
- Save
Citations (0)
Abstract 4369: Preclinical mechanistic PK/PD-efficacy modeling for AZD9833, a novel next generation oral SERD, to support dose selection during early clinical development

2020 Epidemiology
Show All
- Source
- Cite
- Save
Citations (0)
Tricyclic Indazoles—A Novel Class of Selective Estrogen Receptor Degrader Antagonists

2019 Journal of Medicinal Chemistry
Show All
- Source
- Cite
- Save
Citations (18)
PO-491 Single-cell phenotypic profiling of breast cancerpatient-derived tumour xenografts using mass cytometry

2018
Show All
- Source
- Cite
- Save
Citations (0)
Combined Inhibition of mTOR and CDK4/6 Is Required for Optimal Blockade of E2F Function and Long-term Growth Inhibition in Estrogen Receptor–positive Breast Cancer

2018 Molecular Cancer Therapeutics
Show All
- Source
- Cite
- Save
Citations (70)
Inhibition of PI3Kβ Signaling with AZD8186 Inhibits Growth of PTEN-Deficient Breast and Prostate Tumors Alone and in Combination with Docetaxel

2015 Molecular Cancer Therapeutics
Show All
- Source
- Cite
- Save
Citations (46)
Abstract DDT01-03: Discovery and pre-clinical pharmacology of AZD9496: An oral, selective estrogen receptor down-regulator (SERD)

2015 Cancer Research
Show All
- Source
- Cite
- Save
Citations (2)
A Novel Oral Selective Estrogen Receptor Down-regulator, AZD9496, drives Tumour Growth Inhibition in Estrogen Receptor positive and ESR1 Mutant Models

2015
Show All
- Source
- Cite
- Save
Citations (0)