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Edward L. Schwartz

Albert Einstein College of Medicine

66

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Abstract 2928: Evaluating Cks1-Skp2 interface as an effective therapeutic target forRB1-deficient metastatic castration-resistant prostate cancer (mCRPC)

2021 Tumor Biology
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Abstract 2008: Targeting SKP2 by p27 Inhibits stemness and prolong the survival in osteosarcoma

2021
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Abstract 5930: Targeting Skp2 in synovial sarcoma reduces tumor-initiating properties and promotes apoptosis

2020
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Abstract 1060: Genetic and pharmacologic inhibition of Skp2, an E3 ubiquitin ligase and RB1-target, has antitumor activity in RB1-deficient human and mouse small cell lung cancer (SCLC)

2020 Cancer Research
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Skp2 Depletion Reduces Tumor-Initiating Properties and Promotes Apoptosis in Synovial Sarcoma.

2020 Translational Oncology
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Abstract 3306: Inhibition of ribosomal protein S6 (rpS6) phosphorylation and cell proliferation by a novel chloroquine analog in lung cancer cells

2017 Cancer Research
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Abstract 1012: Discovery and synthesis of novel autophagy inhibitors with anti-proliferative activity in lung and pancreatic cancer cells

2015 Cancer Research
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RICTOR amplification defines a novel subset of patients with lung cancer who may benefit from treatment with mTORC1/2 inhibitors

2015 Cancer Discovery
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335 RICTOR amplification as a novel molecular target for the treatment of lung cancer

2014 European Journal of Cancer
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Abstract 2033: Identification of a novel genetic abnormality, the amplification of rictor (rapamycin-insensitive companion of mTOR), in a patient with non-small cell lung cancer.

2013 Cancer Research
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