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Takashi Asahi
Takashi Asahi
Daiichi Sankyo
Biochemistry
Chemistry
Anaerobic glycolysis
PKM2
Binding site
2
Papers
31
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2024
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Discovery of a Potent, Selective, and Orally Available MTHFD2 Inhibitor (DS18561882) with In Vivo Anti-Tumor Activity
2019
Journal of Medicinal Chemistry
Junya Kawai
Tadashi Toki
Masahiro Ota
Hidekazu Inoue
Yoshimi Takata
Takashi Asahi
Makoto Suzuki
Takashi Shimada
Kaori Ono
Kanae Suzuki
Sachiko Takaishi
Hitoshi Ohki
Satoshi Matsui
Shinji Tsutsumi
Yasuhide Hirota
Kiyoshi Nakayama
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Citations (16)
Discovery and structure-guided fragment-linking of 4-(2,3-dichlorobenzoyl)-1-methyl-pyrrole-2-carboxamide as a pyruvate kinase M2 activator
2017
Bioorganic & Medicinal Chemistry
Yumi Matsui
Isao Yasumatsu
Takashi Asahi
Takahiro Kitamura
Kazuo Kanai
Osamu Ubukata
Hitoshi Hayasaka
Sachiko Takaishi
Hiroyuki Hanzawa
Shin‐ichi Katakura
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Citations (15)
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