author-photo

Lynsie Almeida

AstraZeneca

16

Papers

360

Citations

Citation Trend

Filter By

Papers (13) Sort By

Journal Conference Others

Pyrimidinone Nicotinamide Mimetics as Selective Tankyrase and Wnt Pathway Inhibitors Suitable for in Vivo Pharmacology

2015 ACS Medicinal Chemistry Letters
Show All
- Source
- Cite
- Save
Citations (35)
Discovery of AZ0108, an orally bioavailable phthalazinone PARP inhibitor that blocks centrosome clustering

2015 Bioorganic & Medicinal Chemistry Letters
Show All
- Source
- Cite
- Save
Citations (38)
Discovery of 1-methyl-1H-imidazole derivatives as potent Jak2 inhibitors.

2014 Journal of Medicinal Chemistry
Show All
- Source
- Cite
- Save
Citations (39)
Discovery of Checkpoint Kinase Inhibitor (S)-5-(3-Fluorophenyl)-N-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide (AZD7762) by Structure-Based Design and Optimization of Thiophenecarboxamide Ureas.

2012 Journal of Medicinal Chemistry
Show All
- Source
- Cite
- Save
Citations (50)
Abstract 5196: The discovery of small molecule inhibitors of Tankyrases 1 and 2, which modulate Axin homeostasis and inhibit Wnt signaling in vivo

2011 Cancer Research
Show All
- Source
- Cite
- Save
Citations (0)
In vitro and in vivo evaluation of 6-aminopyrazolyl-pyridine-3-carbonitriles as JAK2 kinase inhibitors.

2011 Bioorganic & Medicinal Chemistry Letters
Show All
- Source
- Cite
- Save
Citations (12)
Discovery of 5-Chloro-N2-[(1S)-1-(5-Fluoropyrimidin-2-Yl) Ethyl]-N4-(5-Methyl-1H-Pyrazol-3-Yl)Pyrimidine-2,4-Diamine (Azd1480) as a Novel Inhibitor of the Jak/Stat Pathway

2011 Journal of Medicinal Chemistry
Show All
- Source
- Cite
- Save
Citations (103)
Discovery of pyrazol-3-ylamino pyrazines as novel JAK2 inhibitors.

2009 Bioorganic & Medicinal Chemistry Letters
Show All
- Source
- Cite
- Save
Citations (23)
Derivatives of amino thiazolyl-pyrimidine and its use for the treatment of cancer.

2008
Show All
- Source
- Cite
- Save
Citations (0)
Composés chimiques 831

2008
Show All
- Source
- Cite
- Save
Citations (0)