author-photo

Derek Ogg

AstraZeneca

39

Papers

598

Citations

Citation Trend

Filter By

Papers (32) Sort By

Journal Conference Others

Crystal structure of the kinase domain of human c-KIT in complex with a type-II inhibitor

2020
Show All
- Source
- Cite
- Save
Citations (0)
Crystal structure of the kinase domain of human c-KIT with a cyclic imidate inhibitor covalently bound to Cys788

2020
Show All
- Source
- Cite
- Save
Citations (0)
Structure-based design and pharmacokinetic optimization of covalent allosteric inhibitors of the mutant GTPase KRASG12C

2020 Journal of Medicinal Chemistry
Show All
- Source
- Cite
- Save
Citations (17)
Crystal structure of the kinase domain of human c-KIT in complex with a type-II inhibitor bearing an acrylamide

2020
Show All
- Source
- Cite
- Save
Citations (0)
Crystal structure of the KDR (VEGFR2) kinase domain in complex with a type-II inhibitor

2020
Show All
- Source
- Cite
- Save
Citations (0)
The extracellular domain of G6b-B in complex with Fab fragment and DP12 heparin oligosaccharide.

2019
Show All
- Source
- Cite
- Save
Citations (0)
Heparan sulfates are critical regulators of the inhibitory megakaryocyte-platelet receptor G6b-B.

2019 eLife
Show All
- Source
- Cite
- Save
Citations (15)
Author response: Heparan sulfates are critical regulators of the inhibitory megakaryocyte-platelet receptor G6b-B

2019 eLife
Show All
- Source
- Cite
- Save
Citations (0)
Crystal structure of human KDR (VEGFR2) kinase domain in complex with AZD3229-analogue (compound 23)

2018
Show All
- Source
- Cite
- Save
Citations (0)
Discovery of N-(4-{[5-Fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]amino}phenyl)-2-[4-(propan-2-yl)-1 H-1,2,3-triazol-1-yl]acetamide (AZD3229), a Potent Pan-KIT Mutant Inhibitor for the Treatment of Gastrointestinal Stromal Tumors.

2018 Journal of Medicinal Chemistry
Show All
- Source
- Cite
- Save
Citations (22)