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Juan A. Sánchez-Arias

University of Navarra

23

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467

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Design and Synthesis of Novel Epigenetic Inhibitors Targeting Histone Deacetylases, DNA Methyltransferase 1, and Lysine Methyltransferase G9a with In Vivo Efficacy in Multiple Myeloma.

2021 Journal of Medicinal Chemistry
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A Case Control Study Demonstrates an Increase in Plasma Amylin Associated with Chronic Migraine

2020 Social Science Research Network
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Amylin as a potential link between type 2 diabetes and alzheimer disease.

2019 Annals of Neurology
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Taking Advantage of the Selectivity of Histone Deacetylases and Phosphodiesterase Inhibitors to Design Better Therapeutic Strategies to Treat Alzheimer’s Disease

2019 Frontiers in Aging Neuroscience
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Discovery of in Vivo Chemical Probes for Treating Alzheimer’s Disease: Dual Phosphodiesterase 5 (PDE5) and Class I Histone Deacetylase Selective Inhibitors

2019 ACS Chemical Neuroscience
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Multitarget Approach for the Treatment of Alzheimer’sDisease: Inhibition of Phosphodiesterase 9 (PDE9) and Histone Deacetylases(HDACs) Covering Diverse Selectivity Profiles

2019 ACS Chemical Neuroscience
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Design, synthesis, biological evaluation and in vivo testing of dual phosphodiesterase 5 (PDE5) and histone deacetylase 6 (HDAC6)-selective inhibitors for the treatment of Alzheimer's disease

2018 European Journal of Medicinal Chemistry
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Discovery of Reversible DNA Methyltransferase and Lysine Methyltransferase G9a Inhibitors with Antitumoral in Vivo Efficacy

2018 Journal of Medicinal Chemistry
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GLUCOCEREBROSIDASE MUTATIONS AND SYNUCLEINOPATHIES. POTENTIAL ROLE OF STERYLGLUCOSIDES AND RELEVANCE OF STUDYING BOTH GBA1 AND GBA2 GENES.

2018 Frontiers in Neuroanatomy
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A First-in-Class Small-Molecule that Acts as a Dual Inhibitor of HDAC and PDE5 and that Rescues Hippocampal Synaptic Impairment in Alzheimer’s Disease Mice

2017 Neuropsychopharmacology
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Citations (62)