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J. Wade Harper

Georgia Institute of Technology

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Inhibition of human leukocyte elastase, cathepsin G, chymotrypsin A alpha, and porcine pancreatic elastase with substituted isobenzofuranones and benzopyrandiones.

1985 Biochemistry
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Reaction of serine proteases with substituted 3-alkoxy-4-chloroisocoumarins and 3-alkoxy-7-amino-4-chloroisocoumarins: new reactive mechanism-based inhibitors.

1985 Biochemistry
- J. Wade Harper
- James C. Powers
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Reaction of serine proteases with substituted isocoumarins: discovery of 3,4-dichloroisocoumarin, a new general mechanism based serine protease inhibitor.

1985 Biochemistry
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Mammalian chymotrypsin-like enzymes.Comparative reactivities of rat mast cell proteases, human and dog skin chymases, and human cathepsin G with peptide 4-nitroanilide substrates and with peptide chloromethyl ketone and sulfonyl fluoride inhibitors

1985 Biochemistry
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New mechanism based serine protease inhibitors: inhibition of human leukocyte elastase, porcine pancreatic elastase, human leukocyte cathepsin G, and chymotrypsin by 3-chloroisocoumarin and 3,3-dichlorophthalide

1983 Journal of the American Chemical Society
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Reaction of peptide thiobenzyl esters with mammalian chymotrypsinlike enzymes: A sensitive assay method

1981 Analytical Biochemistry
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Citations (34)