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Mark R. Player

Johnson & Johnson Pharmaceutical Research and Development
University of South Carolina
Janssen Pharmaceutica

89

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Discovery of a Novel Potent GPR40 Full Agonist

2018 Bioorganic & Medicinal Chemistry Letters
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Fasiglifam (TAK-875): Mechanistic Investigation and Retrospective Identification of Hazards for Drug Induced Liver Injury

2018 Toxicological Sciences
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FFAR1 Agonism Restores Insulin Secretion in Rodents, Human Islets, and Diabetic Monkeys

2018 Diabetes
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Discovery of novel benzo[b]thiophene tetrazoles as non-carboxylate GPR40 agonists

2017 Bioorganic & Medicinal Chemistry Letters
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Agonistes de gpr40 pour le traitement du diabète de type 2

2016
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Discovery of novel potent imidazo[1,2-b]pyridazine PDE10a inhibitors

2016 Bioorganic & Medicinal Chemistry Letters
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Benzo[d]imidazole Transient Receptor Potential Vanilloid 1 Antagonists for the Treatment of Pain: Discovery of trans-2-(2-{2-[2-(4-Trifluoromethyl-phenyl)-vinyl]-1H-benzimidazol-5-yl}-phenyl)-propan-2-ol (Mavatrep)

2015 Journal of Medicinal Chemistry
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Process Development for Scale-Up of a Novel 3,5-Substituted Thiazolidine-2,4-dione Compound as a Potent Inhibitor for Estrogen-Related Receptor 1

2014 Organic Process Research & Development
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Transient receptor potential melastatin 8 channel inhibition potentiates the hypothermic response to transient receptor potential vanilloid 1 activation in the conscious mouse

2014 Critical Care Medicine
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Shivering and tachycardic responses to external cooling in mice are substantially suppressed by TRPV1 activation but not by TRPM8 inhibition

2013 American Journal of Physiology-regulatory Integrative and Comparative Physiology
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Citations (28)