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Wherly P. Hoffman

Eli Lilly and Company

31

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699

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Novel Small Molecules Targeting the Intrinsically Disordered Structural Ensemble of α-Synuclein Protect Against Diverse α-Synuclein Mediated Dysfunctions.

2019
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In Vitro Testing: Micronucleus Test

2018
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Effects of single and multiple dose oral administration of ELND006, a novel APP-selective gamma-secretase inhibitor, on amyloid-β concentrations in the brain and CSF of cynomolgus monkeys

2010 Alzheimers & Dementia
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Estimating leukocyte, platelet, and erythrocyte counts in rats by blood smear examination

2009 Veterinary Clinical Pathology
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Non-clinical safety pharmacology study submission—Data standards and statistical analyses

2009 Journal of Pharmacological and Toxicological Methods
- Wherly P. Hoffman
- Mary Jeanne Kallman
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Refinement of the dosage and dosing schedule of ketoprofen for postoperative analgesia in Sprague-Dawley rats

2008 Lab Animal
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Overall Type I Error Rate and Power of Multiple Dunnett's Tests on Rodent Body Weights in Toxicology Studies

2008 Journal of Biopharmaceutical Statistics
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Quantitative assessment of cumulative carcinogenic risk for multiple genotoxic impurities in a new drug substance.

2008 Regulatory Toxicology and Pharmacology
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Duration of effects on clinical parameters and referred hyperalgesia in rats after abdominal surgery and multiple doses of analgesic

2005 Comparative Medicine
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Exacerbation of Cerebral Amyloid Angiopathy-Associated Microhemorrhage in Amyloid Precursor Protein Transgenic Mice by Immunotherapy Is Dependent on Antibody Recognition of Deposited Forms of Amyloid β

2005 The Journal of Neuroscience
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Citations (283)