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Ralf Schwandner

Amgen

15

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1191

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Differing roles for short chain fatty acids and GPR43 agonism in the regulation of intestinal barrier function and immune responses

2017 PLOS ONE
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Utilization of Human Nuclear Receptors as an Early Counter Screen for Off-Target Activity: A Case Study with a Compendium of 615 Known Drugs

2015 Toxicological Sciences
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Activation of FFA1 mediates GLP-1 secretion in mice. Evidence for allosterism at FFA1.

2013 Molecular and Cellular Endocrinology
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Mutational analysis of G-protein coupled receptor--FFA2.

2011 Biochemical and Biophysical Research Communications
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STK33 Kinase Activity Is Nonessential in KRAS-Dependent Cancer Cells

2011 Cancer Research
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Abstract 253: Identification of STK33 kinase inhibitors for the validation of a synthetic lethal relationship between STK33 and mutant KRAS

2011 Cancer Research
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Allosteric rescuing of loss‐of‐function FFAR2 mutations

2010 FEBS Letters
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The first synthetic agonists of FFA2: Discovery and SAR of phenylacetamides as allosteric modulators

2010 Bioorganic & Medicinal Chemistry Letters
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High Throughput Screening for Orphan and Liganded GPCRs

2008 Combinatorial Chemistry & High Throughput Screening
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Discovery of potent LPA2 (EDG4) antagonists as potential anticancer agents

2008 Bioorganic & Medicinal Chemistry Letters
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Citations (35)