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Junhua Fan

Biogen Idec

8

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239

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Structure-based design of low-nanomolar PIM kinase inhibitors

2015 Bioorganic & Medicinal Chemistry Letters
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Structure-based design of 2,6,7-trisubstituted-7H-pyrrolo[2,3-d]pyrimidines as Aurora kinases inhibitors.

2012 Bioorganic & Medicinal Chemistry Letters
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Synthesis, SAR and biological evaluation of 1,6-disubstituted-1H-pyrazolo[3,4-d]pyrimidines as dual inhibitors of Aurora kinases and CDK1.

2012 Bioorganic & Medicinal Chemistry Letters
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Design, synthesis, and biological evaluation of pyrazolopyrimidine-sulfonamides as potent multiple-mitotic kinase (MMK) inhibitors (part I).

2011 Bioorganic & Medicinal Chemistry Letters
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Dimeric ansamycins—A new class of antitumor Hsp90 modulators with prolonged inhibitory activity

2007 International Journal of Cancer
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7'-substituted benzothiazolothio- and pyridinothiazolothio-purines as potent heat shock protein 90 inhibitors.

2006 Journal of Medicinal Chemistry
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Identification of new biomarkers for clinical trials of Hsp90 inhibitors

2006 Molecular Cancer Therapeutics
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Ansamycines a proprietes pharmacologiques et biologiques ameliorees

2003
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