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Beth Ann McKenna

Cephalon

16

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389

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1-Thia-4,7-diaza-spiro[4.4]nonane-3,6-dione: A Structural Motif for 5-hydroxytryptamine 6 Receptor Antagonism

2014 Chemical Biology & Drug Design
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In search of potent 5-HT6 receptor inverse agonists.

2014 Chemical Biology & Drug Design
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Discovery of 7-arylsulfonyl-1,2,3,4, 4a,9a-hexahydro-benzo[4,5]furo[2,3-c]pyridines: Identification of a potent and selective 5-HT6 receptor antagonist showing activity in rat social recognition test

2012 Bioorganic & Medicinal Chemistry Letters
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Glycine transporter (GlyT1) inhibitors with reduced residence time increase prepulse inhibition without inducing hyperlocomotion in DBA/2 mice

2010 Biochemical Pharmacology
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Dimebolin is a 5-HT6 antagonist with acute cognition enhancing activities.

2009 Biochemical Pharmacology
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Successful identification of glycine transporter inhibitors using an adaptation of a functional cell-based assay.

2009 Journal of Biomolecular Screening
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A Homogeneous Assay to Assess GABA Transporter Activity

2005 Current protocols in pharmacology
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Inhibition of mixed lineage kinase 3 attenuates MPP+-induced neurotoxicity in SH-SY5Y cells

2004 Brain Research
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D-amino acid containing, high-affinity inhibitors of recombinant human calpain I

1998 Journal of Medicinal Chemistry
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Exploration of the importance of the P2-P3-NHCO-moiety in a potent di- or tripeptide inhibitor of calpain I: insights into the development of nonpeptidic inhibitors of calpain I.

1998 Bioorganic & Medicinal Chemistry
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Citations (11)