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Joan G. Wilson

GlaxoSmithKline

12

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3031

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The Effect of PPARα, PPARδ, PPARγ, and PPARpan Agonists on Body Weight, Body Mass, and Serum Lipid Profiles in Diet-Induced Obese AKR/J Mice

2007 Ppar Research
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Identification of a Nonsteroidal Liver X Receptor Agonist through Parallel Array Synthesis of Tertiary Amines

2002 Journal of Medicinal Chemistry
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Regulation of cholesterol homeostasis by the liver X receptors in the central nervous system.

2002 Molecular Endocrinology
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Ileal bile acid transporter inhibition, CYP7A1 induction, and antilipemic action of 264W94

2002 Journal of Lipid Research
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Liver X Receptor (LXR) Regulation of the LXRα Gene in Human Macrophages

2001 Journal of Biological Chemistry
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Effects of PPARγ agonist treatment on cardiac metabolic substrate utilization in fed and fasted rats

2001 Journal of Molecular and Cellular Cardiology
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GI262570 prevents and reverses the progression of early diabetes in Zucker diabetic rats

2000 Diabetes Research and Clinical Practice
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Identification of a chemical tool for the orphan nuclear receptor FXR

2000 Journal of Medicinal Chemistry
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A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis.

2000 Molecular Cell
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A Ureido-Thioisobutyric Acid (GW9578) Is a Subtype-Selective PPARα Agonist with Potent Lipid-Lowering Activity

1999 Journal of Medicinal Chemistry
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Citations (123)