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Jakob S. Pallesen
Jakob S. Pallesen
University of Copenhagen
Chemistry
KEAP1
Transcription factor
Kelch-Like ECH-Associated Protein 1
Biochemistry
5
Papers
94
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Deconstructing Noncovalent Kelch-like ECH-Associated Protein 1 (Keap1) Inhibitors into Fragments to Reconstruct New Potent Compounds.
2021
Journal of Medicinal Chemistry
Jakob S. Pallesen
Dilip Narayanan
Kim T. Tran
Sara Marie Øie Solbak
Giuseppe Marseglia
Louis M.E. Sørensen
Lars Jakobsen Høj
Federico Munafò
Rosa M. C. Carmona
Anthony D. Garcia
Haritha L. Desu
Roberta Brambilla
Tommy N. Johansen
Grzegorz M. Popowicz
Michael Sattler
Michael Gajhede
Anders Bach
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Citations (5)
N-(7-(1H-imidazol-1-yl)-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl)benzamide - a new kainate receptor selective antagonist and analgesic: Synthesis, X-ray crystallography, structure-affinity relationships, in vitro and in vivo pharmacology
2019
ACS Chemical Neuroscience
Stine Møllerud
Rie Bager Hansen
Jakob S. Pallesen
Piero Temperini
Diletta Pasini
Jan Bornholt
Birgitte Nielsen
Esmira Mamedova
Paulina Chalupnik
Ana V. Paternain
Juan Lerma
Marta Diaz-delCastillo
Jesper T. Andreasen
Karla Frydenvang
Jette S. Kastrup
Tommy N. Johansen
Darryl S. Pickering
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Citations (3)
A Comparative AssessmentStudy of Known Small-MoleculeKeap1−Nrf2 Protein–Protein Interaction Inhibitors: ChemicalSynthesis, Binding Properties, and Cellular Activity
2019
Journal of Medicinal Chemistry
Kim T. Tran
Jakob S. Pallesen
Sara Marie Øie Solbak
Dilip Narayanan
Amina Baig
Jie Zang
Alejandro Aguayo-Orozco
Rosa M. C. Carmona
Anthony D. Garcia
Anders Bach
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Citations (36)
A Prodrug Approach Involving In Situ Depot Formation to Achieve Localized and Sustained Action of Diclofenac After Joint Injection
2014
Journal of Pharmaceutical Sciences
Mette Thing
Li Ågårdh
Susan Weng Larsen
Rune Skovgaard Rasmussen
Jakob S. Pallesen
Nina Mertz
Jesper L. Kristensen
Martin Hansen
Jesper Østergaard
Claus Larsen
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Citations (7)
1