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John E. Starrett

Bristol-Myers Squibb

86

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3417

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Composés tricycliques utilisés en tant qu'agents anticancéreux

2016
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The Synthesis and Structure—Activity Relationships of 1,3-Diaryl 1,2,4-(4H)-Triazol-5-ones: A New Class of Calcium-Dependent, Large Conductance, Potassium (Maxi-K) Channel Opener Targeted for Urge Urinary Incontinence.

2010 ChemInform
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The Discovery of Novel Openers of Ca2+-Dependent Large-Conductance Potassium Channels: Pharmacophore Search and Physiological Evaluation of Flavonoids.

2010 ChemInform
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The Synthesis and Structure-Activity Relationships of 4-Aryl-3-aminoquinolin-2-ones: A New Class of Calcium-Dependent, Large Conductance, Potassium (Maxi-K) Channel Openers Targeted for Post-Stroke Neuroprotection.

2010 ChemInform
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3-[(5-Chloro-2-hydroxyphenyl)methyl]-5-[4-(trifluoromethyl)phenyl ]-1,3,4-oxadiazol-2(3H)-one, BMS-191011: Opener of Large-Conductance Ca2+-Activated Potassium (Maxi-K) Channels, Identification, Solubility, and SAR

2007 Journal of Medicinal Chemistry
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Chemical Genetics Reveals an RGS/G-Protein Role in the Action of a Compound

2006 PLOS Genetics
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(S,E)-N-[1-(3-Heteroarylphenyl)ethyl]-3-(2-fluorophenyl)acrylamides: synthesis and KCNQ2 potassium channel opener activity

2005 Bioorganic & Medicinal Chemistry Letters
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Analogues (Ib)-(Ic) of a Potent Maxi-K Potassium Channel Opener (Ia) with an Improved Inhibitory Profile Toward Cytochrome P450 Isozymes.

2005 ChemInform
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Rational design of RAR-selective ligands revealed by RARβ crystal stucture

2004 EMBO Reports
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The synthesis and structure–activity relationships of 3-amino-4-benzylquinolin-2-ones: discovery of novel KCNQ2 channel openers

2004 Bioorganic & Medicinal Chemistry Letters
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Citations (19)