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Panos Lehouritis

University College Cork

12

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323

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In situ biomolecule production by bacteria; a synthetic biology approach to medicine

2018 Journal of Controlled Release
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Activation of multiple chemotherapeutic prodrugs by the natural enzymolome of tumour-localised probiotic bacteria.

2016 Journal of Controlled Release
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Attenuated Salmonella targets prodrug activating enzyme carboxypeptidase G2 to mouse melanoma and human breast and colon carcinomas for effective suicide gene therapy.

2008 Clinical Cancer Research
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Self-immolative nitrogen mustards prodrugs cleavable by carboxypeptidase G2 (CPG2) showing large cytotoxicity differentials in GDEPT

2003 Journal of Medicinal Chemistry
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Gene regulation in cancer gene therapy strategies

2003 Current Medicinal Chemistry
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