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Anke Unger

23

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635

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Small-molecule inhibitors of human mitochondrial DNA transcription

2020 Nature
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Targeting Her2-insYVMA with Covalent Inhibitors – A Focused Compound Screening and Structure-Based Design Approach

2020 Journal of Medicinal Chemistry
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Structure of human mitochondrial RNA polymerase in complex with IMT inhibitor.

2020
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Inhibition of Osimertinib-Resistant Epidermal Growth Factor Receptor EGFR-T790M/C797S

2019 Chemical Science
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Chronic high dose P2X7 receptor inhibition exacerbates cancer-induced bone pain

2019 European Journal of Pharmacology
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Potent anti-leukemic activity of a specific cyclin-dependent kinase 9 inhibitor in mouse models of chronic lymphocytic leukemia

2018 Oncotarget
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Combined Human Genome-wide RNAi and Metabolite Analyses Identify IMPDH as a Host-Directed Target against Chlamydia Infection

2018 Cell Host & Microbe
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Structure-Guided Development of Covalent and Mutant-Selective Pyrazolopyrimidines to Target T790M Drug Resistance in Epidermal Growth Factor Receptor

2017 Journal of Medicinal Chemistry
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Discovery of N-{4-[5-(4-Fluorophenyl)-3-methyl-2-methylsulfanyl-3H-imidazol-4-yl]-pyridin-2-yl}-acetamide (CBS-3595), a Dual p38α MAPK/PDE-4 Inhibitor with Activity against TNFα-Related Diseases

2017 Journal of Medicinal Chemistry
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Abstract 222: Inhibitors of mitochondrial transcription (IMT) specifically affect cancer cell proliferation

2016 Cancer Research
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