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Sarah Meade

Harvard University

4

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275

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A Brain-Permeable Small Molecule Reduces Neuronal Cholesterol by Inhibiting Activity of Sirtuin 2 Deacetylase

2011 ACS Chemical Biology
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Evaluation of Histone Deacetylases as Drug Targets in Huntington's Disease models Study of HDACs in brain tissues from R6/2 and CAG140 knock-in HD mouse models and human patients and in a neuronal HD cell model.

2010 PLOS Currents
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Identification of Tri‐ and Tetracyclic Pyrimidinediones as Sirtuin Inhibitors

2010 ChemMedChem
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Study of 1,4-dihydropyridine structural scaffold: Discovery of novel sirtuin activators and inhibitors

2009 Journal of Medicinal Chemistry
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