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Sergio Valente

Sapienza University of Rome

161

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Polycomb Repressive Complex 2 Modulation through the Development of EZH2-EED Interaction Inhibitors and EED Binders.

2021 Journal of Medicinal Chemistry
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Editorial: New Approaches to Tackle EMT and Fibrosis: From Epigenetics to Nanotechnology.

2021 Frontiers in Pharmacology
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Partial resistance to HDAC inhibitors in FAPs of dystrophic muscles at late stages of disease is associated to epigenetic and transcriptional features of cellular senescence

2021 bioRxiv
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Editorial: Natural Product Epigenetic Modulators and Inhibitors

2021 Frontiers in Pharmacology
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Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2-EED Interaction.

2021 Journal of Medicinal Chemistry
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Metabolic Rewiring by Loss of Sirt5 Promotes Kras-Induced Pancreatic Cancer Progression.

2021 Gastroenterology
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Targeting the scaffolding role of LSD1 (KDM1A) poises acute myeloid leukemia cells for retinoic acid-induced differentiation.

2020 Science Advances
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Novel Quinoline Compounds Active in Cancer Cells through Coupled DNA Methyltransferase Inhibition and Degradation

2020 Cancers
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Novel Pyridine-Based Hydroxamates and 2'-Aminoanilides as Histone Deacetylase Inhibitors: Biochemical Profile and Anticancer Activity.

2020 ChemMedChem
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A closer look into NADPH oxidase inhibitors: Validation and insight into their mechanism of action

2020 Redox biology
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Citations (22)