Two undescribed monoterpenoids from the fruit of Gardenia jasminoides Ellis
0
Citation
16
Reference
10
Related Paper
Keywords:
Gardenia jasminoides
Gardenia
The fruit of Gardenia jasminoides Ellis has been traditionally used as a Chinese medicine for centuries in China, as well as in other Asian countries [1]. The major and characteristic constituents of Gardenia fruit are iridoid glycosides such as geniposide, gardenoside, genipin-1-β-gentiobioside, geniposidic acid, acetylgeniposide, scandoside methyl ester, shanzhiside and gardoside. Modern clinical and pharmacological research has revealed that Gardenia fruit has anti-inflammatory properties, cytotoxic effects, as well as protective against oxidative damage [1,2]. In the Chinese Pharmacopoeia a topical application of the fruit of gardenia, powdered and mixed with water is reported [8]. Gardenia fruit also represents the principal effective ingredient of a preparation with antiinflammatory and analgesic properties, „Zhongtong Caji“, a kind of liniment for external use, formulated with more than ten different herbal drugs [3].
Gardenia jasminoides
Gardenia
Genipin
Pharmacopoeia
Cite
Citations (1)
Gardenia jasminoides
Gardenia
Crocetin
Cite
Citations (57)
Gardenia
Gardenia jasminoides
Genipin
Crocetin
Ames test
Cite
Citations (91)
As a natural and functional pigment, Gardenia (Gardenia jasminoides Ellis) yellow pigment is becoming more and more popular. In this paper, Gardenia yellows characteristics and deterioration of quality , especially its extraction and purification, are reviewed. Some suggestions are given on the production of high-quality Gardenia yellow pigment.
Gardenia jasminoides
Gardenia
Cite
Citations (1)
This thesis introduces main functions about gardenia jasminodes,and analyzes the characteristics of the refining methods of the gardenia yellow pigment.So far,the main refining methods of high color price have been macroporous resin,and the new technology like membrane separation are recent hot research.
Gardenia jasminoides
Gardenia
Refining (metallurgy)
Cite
Citations (0)
Objective To ascertain the germplasm resources of Gardenia jasminoids in Jiangxi Xingang.Methods To compare its main characteristics and the concentrations of its main chemical components.Results Gardenia jasminoids in Jiangxi Xingang could be divided into nine basic types.The single fruit weights of Xingan No.4,No.5 and No.9 were respectively 2.78,2.42 and 2.84 g,and the corresponding geniposide concentrations were respectively 20.04,28.98 and 38.50/mg/g.Conclusion The types of Gardenia jasminoids in Jiangxi Xingang are abundant.No.4,No.5 and 9 hao are good types and can be widely cultivated.
Gardenia jasminoides
Gardenia
Germ plasm
Cite
Citations (0)
For many centuries, Gardenia (Gardenia jasminoides Ellis) was highly valued as a food homologous Chinese herbal medicine with various bioactive compounds, including crocin I and geniposide. However, the functional mechanism underlying the hypoglycemic effect of gardenia is absent in the literature. To evaluate the effect of gardenia and its different extracts on type 2 diabetes mellitus (T2DM) in in vivo and in vitro experiments, the dried gardenia powder was extracted using 60% ethanol and eluted at different ethanol concentrations to obtain the corresponding purified fragments. After that, the active chemical compositions of the different purified gardenia fragments were analyzed using HPLC. Then, the hypoglycemic effects of the different purified gardenia fragments were compared using in vitro and in vivo experiments. Finally, the different extracts were characterized using UPLC-ESI-QTOF-MS/MS and the mass spectrometric fragmentation pathway of the two main compounds, geniposide and crocin I, were identified. The experimental results indicated that the inhibitory effect of the 40% EGJ (crocin I) on the α-glucosidase was better than the 20% EGJ (geniposide) in vitro. However, the inhibitory effect of geniposide on T2DM was better than crocin I in the animal experiments. The different results in vivo and in vitro presumed potentially different mechanisms between crocin I and geniposide on T2DM. This research demonstrated that the mechanism of hypoglycemia in vivo from geniposide is not only one target of the α-glucosidase but provides the experimental background for crocin I and the geniposide deep processing and utilization.
Gardenia
Gardenia jasminoides
Crocetin
Cite
Citations (9)
Gardenia jasminoides
Gardenia
Flesh
Cite
Citations (0)
This paper made a comprehensive presentation of the origin places,variety and the major components of gardenia.In addition,the pharmacological effects of gardenia and crocin compounds were also discussed in this article.This paper provided a reference of Gardenia jasminoides further development.
Gardenia jasminoides
Gardenia
Cite
Citations (2)
The EtOH extract of gardenia (Gardenia jasminoides Ellis) fruits was previously found to possess potent anti-angiogenic activity in the chick embryo chorioallantoic membrane (CAM) assay. Bioassay-guided fractionation and purification of the EtOH extract yielded an active anti-angiogenic compound, which was determined to be an iridoid glucoside, geniposide, by spectral analyses. Geniposide showed anti-angiogenic activity in a dose-dependent manner. It also exhibited an inhibitory effect in the range of 25 - 100 μM on the growth of the transformed NIH3T3 cell line.
Gardenia jasminoides
Gardenia
Chorioallantoic membrane
Glucoside
Active compound
Cite
Citations (97)