Severity and presentation of allergic reactions during baked milk oral food challenges
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Milk allergy
Cow's milk allergy
Milk protein
Food protein
Beta-lactoglobulin
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Milk protein
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Cow's milk allergy
Cow milk
Milk protein
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Objective: To report the results of open challenge tests performed in children fed with cow’s milk-free diet. Description: Cross-sectional study evaluating cow’s milk open challenge performed under supervision in a hospital setting during 2.5 hours and ambulatory follow-up for 30 days when no immediate reaction occurred. One hundred and twenty-one patients were included, with ages between 4 and 95 months. Cow’s milk open challenge tests were positive in 28 patients (23.1%). A clinical manifestation of cow’s milk allergy different from the one presented at diagnosis occurred in 12 (24.9%) patients with positive challenge. Positive challenge was more frequent (p = 0.042) in patients fed with extensively hydrolyzed formulae or amino acid-based formulae (30.3%) when compared to those fed with other exclusion diets (14.5%). Conclusion: Open challenge allowed the interruption of exclusion diet in a significant proportion of the patients.
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Objective To observe the clinical effecttiveness of whey protein hydrolyzed formula(Nobiyaka) in the patients with eczema caused by cow′s milk allergy.Methods 37 patients with eczema caused by cow′s milk allergy were treated with Nobiyaka for 1 to 12 months instead of ordinary formula milk. The allergic symptoms and nutritional state were compared before and after treatment.Results After the treatment, blood eosinocytes and atopic dermatitis area and severity index(ADASI) decreased significantly in all patients (P0.001). And relative weight increased significantly(P0.005). Full effectiveness was recognized in 22 patients, and effectiveness in 15 patients;3 patients seemed to be intolerant to the formula, who showed dilute stool after the diet treatment.Conclusion Nobiyaka was noticeably effective for the patients with eczema secondary to cow′s milk protein allergy.
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Allergy to cow’s milk proteins is the most common cause of allergic reactions in young children, with a significant impact on the quality of life of children and their families. The most significant biomarker of herbivore milk allergy is allergen-specific IgE (sIgE), which can be assessed both for the whole allergen (for example, cow’s milk (CM), mare’s milk, goat’s milk, etc.) and a specific molecule, included in their composition. This article focuses on the use of sIgE in infants with suspected cow’s milk protein allergy.
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and Longo et al [7
Cow's milk allergy
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Beta-lactoglobulin
Cow milk
Food hypersensitivity
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Cow milk protein allergy not only belongs to the region of food safety,but also involves clinical medicine fields.With the develop-ment of society,cow milk protein allergy gets more and more attention.This paper summarizes the progress in mechanism,classification,clinical symptom,allergens and allergen modification of cow milk protein allergy.
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By Rui Martins, Mark P. Connolly & 1 more. To compare the cost-effectiveness of hypoallergenic formulas in reducing allergic manifestations and promoting immune tolerance in infants with immunoglobulin E (IgE)-mediated symptoms of cow’s milk protein allergy.
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Milk allergy
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