Open challenge for the diagnosis of cow's milk protein allergy Teste de desencadeamento aberto no diagnóstico de alergia à proteína do leite de vaca
Fernanda Ferreira CorrêaMário César VieiraDanielle Reis YamamotoPatrícia da GraçaLeite SperidiãoMauro Batista de Morais
0
Citation
10
Reference
0
Related Paper
Abstract:
Objective: To report the results of open challenge tests performed in children fed with cow’s milk-free diet. Description: Cross-sectional study evaluating cow’s milk open challenge performed under supervision in a hospital setting during 2.5 hours and ambulatory follow-up for 30 days when no immediate reaction occurred. One hundred and twenty-one patients were included, with ages between 4 and 95 months. Cow’s milk open challenge tests were positive in 28 patients (23.1%). A clinical manifestation of cow’s milk allergy different from the one presented at diagnosis occurred in 12 (24.9%) patients with positive challenge. Positive challenge was more frequent (p = 0.042) in patients fed with extensively hydrolyzed formulae or amino acid-based formulae (30.3%) when compared to those fed with other exclusion diets (14.5%). Conclusion: Open challenge allowed the interruption of exclusion diet in a significant proportion of the patients.Keywords:
Cow's milk allergy
Milk allergy
Milk protein
Cow milk
Elimination diet
Cite