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    In disposal the chloride profiles of concrete after a period of exposure,the manners of collecting concrete powder,measuring and expressing chloride contents all can influence the evaluating results.In different periods and different environments,the forms of chloride profiles are different.It's not reasonable to use the apparent surface concentration as main coefficient in evaluating chloride invading character.By analyzing and comparing,an approach which using interface of convection zone and diffusion zone as the diffusion surface,and using the chloride concentration in interface as diffusion surface concentration is suggested to evaluate invading character of chloride ion and predict lifespan of structure.
    Penetration (warfare)
    Citations (0)
    Thyme with the scientific moniker of Thymus vulgaris has been used in traditional medicine for treatment of respiratory and gastrointestinal disease. Its extract has also been adopted to treat epilepsy and other central nervous system (CNS) disorders. To evaluate the effect of T. vulgaris extract (TVE), the experimental model of memory impairment caused by seizures was performed in rats. Seizures in Wistar rats (200-250 g) were induced with a challenge dose (60 mg/kg) of pentylenetetrazole (PTZ). Animal treated with either TVE (100 mg/kg) or sodium valproate (100 mg/kg) alone or in combination intraperitoneally 30 min before PTZ administration. The effect of memory was assessed using passive avoidance test (PA). At the end of the experiment, the rats were put down painlessly via deep anesthesia and their serums were isolated for oxidant/antioxidant assay (nitric oxide (NO), catalase (CAT), superoxide dismutase (SOD)). PTZ-treated groups revealed memory deficit seizures compared with the control group. TVE exhibited protection at the dose of 100 mg/kg in the PTZ-induced seizures. TVE also reduced seizure-induced memory impairment, which resulted in a significant improvement in memory retention in PA compared with the PTZ-treated group. In addition, TVE treatment protects the seizure-induced memory deficit by lowering NO and restore the antioxidant enzyme CAT and SOD levels. The findings revealed that TVE exhibits significant inhibitory activity and impedes seizure-induced memory impairment by inhibiting oxidative stress damage.
    Memory Impairment
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    The chloride and sulfate exist together in real environment, no matter marine or salts lakes, and the ratio of the chloride to sulfate is varied. To precisely predict the concrete durability under real environment, this paper mainly investigated the influence of sulfate on chloride ions diffuse into hardened cement paste. The Minitab software was used to calculate and design the content of compound impregnating solution in order to fully understand the effect of the concentration of chloride and sulfate on the chloride diffusion depth. The AgNO3-based colorimetric method and acid-soluble chloride test were used to determine the chloride diffusion depth and the chloride penetration profile. The evolution phase distribution from the outer to the inner were characterized by SEM, EDS and XRD. The results showed that chloride diffusion generally increased with increasing concentration of chloride. The presence of sulfates promoted chloride diffusion initially, while it delayed the chloride diffusion in the later. Chloride ions diffused into mortar mainly through ITZ and pores, and reacted with the hydration products to produce Friedel’s salt. Although the diffusion rate of sulfate ions is slow, it can alter the stability of the Friedel’s salt and block the pores, which has a long-term effect on chloride ion diffusion.
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    Although exogenous D-serine has been applied as a neural regulatory intervention in many studies, the role played by D-serine in hippocampal injuries caused by lead exposure remains poorly understood. Rat models of chronic lead exposure were established through the administration of 0.05% lead acetate for 8 weeks. Simultaneously, rats were administered 30 or 60 mg/kg D-serine, intraperitoneally, twice a day. Our results showed that D-serine treatment shortened the escape latency from the Morris water maze, increased the number of times that mice crossed the original platform location, and alleviated the pathological damage experienced by hippocampal neurons in response to lead exposure. Although D-serine administration did not increase the expression levels of the N-methyl-D-aspartate receptor subtype 2B (NR2B) in the hippocampi of lead-exposed rats, 60 mg/kg D-serine treatment restored the expression levels of NR2A, which are reduced by lead exposure. These findings suggested that D-serine can alleviate learning and memory impairments induced by lead exposure and that the underlying mechanism is associated with the increased expression of NR2A in the hippocampus. This study was approved by the Animal Ethics Committee of North China University of Science and Technology, China (approval No. LX2018155) on December 21, 2018.
    Memory Impairment
    Citations (6)
    Two types of solid-state mercury(I) chloride electrodes have been used to determine chloride in the concentration range 0–20 µg l–1. At these low concentrations, more chloride will dissolve from the mercury(I) chloride in the electrode than is present in the sample itself. The extent of the dissolution is controlled, however, by the chloride in the sample. In these circumstances, the electrode potential is linearly related to the concentration of chloride in the sample. With the electrode housed in a flow cell with a thermostatically controlled water jacket, the correlation coefficient between e.m.f. and concentration was always greater than 0.99. The sensitivity (0.18 mV per µg 1–1 of chloride at 25 °C and 0.4–0.5 mV per µg l–1 of chloride at 4 °C) was about ten times greater than that of the silver-silver chloride electrode. Total standard deviations at 10, 5 and 2 µg l–1 of chloride were 0.4, 0.5 and 0.3 µg l–1 of chloride, respectively.
    Silver chloride
    Mercury
    Citations (15)