‘BARCELONA CP’ A case of chronic cyanoacrylate glue
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Purpose To report a case of idiopathic corneal perforation with chronic inflammation in the setting of a persistent cyanoacrylate corneal glue patch lasting 420 days. Observations Cyanoacrylate glue is a fast-acting and effective adhesive which has been utilised in the repair of corneal perforations. Their strength, quick drying, non-biodegradable and anti-microbial properties make them a valuable tool in closing small corneal wounds, often as a temporising measure before definitive management is performed. Complications associated with cyanoacrylate patch include glue toxicity, inflammation, corneal neovascularisation and giant papillary conjunctivitis. Conclusions Cyanoacrylate glue should be considered a transitory measure. It is preferable to remove cyanoacrylate at the end of the treatment unless the glue has self-dislodge. Controversies surround the issue of selecting proper timing for removal of cyanoacrylate glue with no clear consensus.Keywords:
GLUE
Corneal perforation
Cyanoacrylates
Perforation
GLUE
Cyanoacrylates
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A case of asthma due to a short period of work with ethyl-cyanoacrylate glue is reported. The diagnostic method is serial peak flow measurement. The need for preventive precautions in work with cyanoacrylates is proposed.
Cyanoacrylates
GLUE
Occupational Asthma
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GLUE
Corneal perforation
Perforation
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Corneal perforation
Cyanoacrylates
Perforation
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Histoacryl glue (N-butyl-2-cyanoacrylate) has well-established utility in the endoscopic management of gastrointestinal variceal bleeding. The role of Histoacryl glue in non-variceal bleeding is less clear, and there are few articles describing its use in this setting.Six patients with intractable non-variceal gastrointestinal bleeding were managed using injection of Histoacryl glue. All patients had previously failed conventional endostasis and/or interventional angioembolization and were not suitable for emergency salvage surgery due to serious comorbidities or unacceptable anaesthetic risk. An endoscopic Lipiodol-Histoacryl-Lipiodol sandwich injection technique was used in these patients. The clinical outcomes and complications were evaluated.There were four females and two males with a mean age of 55 years. Bleeding lesions included gastric ulcers (n = 2), duodenal ulcers (n = 2), duodenal gastrointestinal stromal tumor (GIST) (n = 1) and rectal ulcers (n = 1). All patients had successful Histoacryl endostasis without the requirement for salvage surgery. There was no treatment-related morbidity and no mortality. Two patients had further bleeding after initial Histoacryl endostasis, which was successfully controlled with further endoscopic Histoacryl injection.Histoacryl endostasis should be included in the treatment algorithm for refractory non-variceal gastrointestinal bleeding.
GLUE
Cyanoacrylates
Refractory (planetary science)
Gastrointestinal bleeding
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GLUE
Cyanoacrylates
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GLUE
Cyanoacrylates
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GLUE
Gastric varices
Cyanoacrylates
Varix
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Purpose: To investigate the effectiveness of cyanoacrylate glue application in cases of corneal perforation or impending perforation due to refractory keratitis. Methods: Cyanoacrylate glue was applied on 6 cases of fungal keratitis, 3 cases of herpetic keratitis, and 3 cases of bacterial keratitis from July 1998 to June 2002. 2 cases were corneal perforations and 10 were impending perforations. Cyanoacrylate glue was applied on stromal melting area including normal epithelium. When fibrovascular tissue grew beneath the glue sufficiently, glue was removed. When glue was sloughed off spontaneously or fibrovascular tissue was found to be insufficient, glue was reapplied. Results: After average follow up of 25 weeks, the corneal surface was stabilized in 11 eyes except 1 case of fungal keratitis that had broad area of stromal melting(5.4mm). After use of glue, process of stromal melting was found to be discontinued. As fibrovascular tissue grew up beneath the glue, corneal surface became stable. Average diameter of stromal melting area and of glue application area was 4.0mm and 4.4mm respectively. Average duration of glue application was 17 weeks. Conclusions: Cyanoacrylate glue application appears to be an effective and convenient method in cases of corneal perforations and impending perforations associated with advanced and extensive fungal, bacterial, and herpetic keratitis with active keratolysis.
GLUE
Corneal perforation
Perforation
Fungal Keratitis
corneal ulcer
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Purpose To report a case of idiopathic corneal perforation with chronic inflammation in the setting of a persistent cyanoacrylate corneal glue patch lasting 420 days. Observations Cyanoacrylate glue is a fast-acting and effective adhesive which has been utilised in the repair of corneal perforations. Their strength, quick drying, non-biodegradable and anti-microbial properties make them a valuable tool in closing small corneal wounds, often as a temporising measure before definitive management is performed. Complications associated with cyanoacrylate patch include glue toxicity, inflammation, corneal neovascularisation and giant papillary conjunctivitis. Conclusions Cyanoacrylate glue should be considered a transitory measure. It is preferable to remove cyanoacrylate at the end of the treatment unless the glue has self-dislodge. Controversies surround the issue of selecting proper timing for removal of cyanoacrylate glue with no clear consensus.
GLUE
Corneal perforation
Cyanoacrylates
Perforation
Cite
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