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    Supplementary Table S4 from FGF401, A First-In-Class Highly Selective and Potent FGFR4 Inhibitor for the Treatment of FGF19-Driven Hepatocellular Cancer
    Andreas WeißFlavia AdlerAlexandra BuhlesChristelle StammRobin A. FairhurstMichael KiffeDario SterkerMario CentelegheMarkus WartmannJacqueline Kinyamu-AkundaHeiko S. SchadtPhilippe CouttetArmin WolfYouzhen WangPatrizia Barzaghi-RinaudoM. MurakamiAudrey KauffmannThomas KnoepfelNicole BuschmannCatherine LeblancRobert MahPascal FuretJutta BlankFrancesco HofmannWilliam R. SellersDiana Graus Porta
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    Abstract:
    <p>Activity of FGF401 in PDXs</p>
    Keywords:
    FGF19
    Hepatocellular cancer
    Table (database)
    Topics:
    Fibroblast Growth Factor Research
    Kruppel-like factors research
    Epigenetics and DNA Methylation
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    Supplementary Table S2 from FGF401, A First-In-Class Highly Selective and Potent FGFR4 Inhibitor for the Treatment of FGF19-Driven Hepatocellular Cancer
    Andreas WeißFlavia AdlerAlexandra BuhlesChristelle StammRobin A. Fairhurst
    <p>Pharmacologic profiling of FGF401 in cancer cell lines</p>
    Hepatocellular cancer
    FGF19
    Table (database)
    Citations (0)
    Supplementary Table S4 from FGF401, A First-In-Class Highly Selective and Potent FGFR4 Inhibitor for the Treatment of FGF19-Driven Hepatocellular Cancer
    Andreas WeißFlavia AdlerAlexandra BuhlesChristelle StammRobin A. Fairhurst
    <p>Activity of FGF401 in PDXs</p>
    FGF19
    Hepatocellular cancer
    Table (database)
    Citations (0)
    Supplementary Table S2 from FGF401, A First-In-Class Highly Selective and Potent FGFR4 Inhibitor for the Treatment of FGF19-Driven Hepatocellular Cancer
    Andreas WeißFlavia AdlerAlexandra BuhlesChristelle StammRobin A. Fairhurst
    <p>Pharmacologic profiling of FGF401 in cancer cell lines</p>
    Hepatocellular cancer
    FGF19
    Profiling (computer programming)
    Citations (0)
    Supplementary Table S4 from FGF401, A First-In-Class Highly Selective and Potent FGFR4 Inhibitor for the Treatment of FGF19-Driven Hepatocellular Cancer
    Andreas WeißFlavia AdlerAlexandra BuhlesChristelle StammRobin A. Fairhurst
    <p>Activity of FGF401 in PDXs</p>
    FGF19
    Hepatocellular cancer
    Table (database)
    Citations (0)
    Risk Analysis of Hepatocellular Carcinoma in Northeast China
    中国癌症研究：英文版 (2009)
    Zhi-fangJia JiaMeng MengSuMiao Miao
    客观长期的肝炎 B 病毒(HBV ) 感染是为 hepatocellular 癌(HCC ) 的一个主要风险因素，这被知道。为 HCC 在风险上估计有另外的因素的 HBV 感染和它的相互作用的效果，基于医院的盒子控制研究在东北中国被执行。有没有肝疾病的证据的 hepatocellular 癌和 432 控制的 384 个盒子全部的方法 A 在学习被注册。血样品被收集检测肝炎 B 病毒(HBV ) 和丙肝病毒(HCV ) 的浆液标记，关于生活方式和家庭肿瘤历史的问询表在所有题目被执行。结果在 hepatocellular 癌盒子中的 HBV 的全部的感染率在非肝疾病控制是 70.8% 和 10.0% 。盒子和控制之间有统计上重要的差别(P<0.0001 )(OR= 22.0；95%CI:15.0 32.3 ) 。相互作用分析显示在有 HCV 感染或白酒消费或家庭 HCC 历史的 HBV 长期的搬运人，为 HCC 的风险增加了(OR=41.1， 95%CI：20.2 83.9， OR=125.0， 95%CI：66.5 235.2；OR=56.9， 95%CI：27.2 119.3 分别地) 。另外，肝炎 B 历史， HCV 感染，肝的肝硬化和 HCC 的家庭历史也是潜在的 HCC 独立风险因素。我们证实了那 HBV 的结论为在东北中国的 67.7% 所有 hepatocellular 癌是为 hepatocellular 癌和报道的一个主要风险因素。HCV 感染，白酒吸入和家庭历史能在长期的 HBV 搬运人为 HCC 提高风险。
    Hepatocellular cancer
    Hepatitis B
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    Supplementary Figure S1 from FGF401, A First-In-Class Highly Selective and Potent FGFR4 Inhibitor for the Treatment of FGF19-Driven Hepatocellular Cancer
    Andreas WeißFlavia AdlerAlexandra BuhlesChristelle StammRobin A. Fairhurst
    <p>FGF401 activity in cancer cell lines</p>
    Hepatocellular cancer
    FGF19
    Citations (0)
    Supplementary Table S3 from FGF401, A First-In-Class Highly Selective and Potent FGFR4 Inhibitor for the Treatment of FGF19-Driven Hepatocellular Cancer
    Andreas WeißFlavia AdlerAlexandra BuhlesChristelle StammRobin A. Fairhurst
    <p>Activity of FGF401, BLU-554 and H3B-6527 in FGF19/FGFR4/KLB+ HCC cell lines</p>
    FGF19
    Hepatocellular cancer
    Table (database)
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    Sorafenib in Advanced Hepatocellular Carcinoma: A Further Step Toward Personalized Therapy of Liver Cancer
    Gastroenterology (2009)
    Massimo Colombo
    Liver Cancer
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    Supplementary Table S1 from FGF401, A First-In-Class Highly Selective and Potent FGFR4 Inhibitor for the Treatment of FGF19-Driven Hepatocellular Cancer
    Andreas WeißFlavia AdlerAlexandra BuhlesChristelle StammRobin A. Fairhurst
    <p>Activity of FGF401 in biochemical kinase assays</p>
    FGF19
    Hepatocellular cancer
    Table (database)
    Citations (0)
    Supplementary Figure S3 from FGF401, A First-In-Class Highly Selective and Potent FGFR4 Inhibitor for the Treatment of FGF19-Driven Hepatocellular Cancer
    Andreas WeißFlavia AdlerAlexandra BuhlesChristelle StammRobin A. Fairhurst
    <p>FGF401 versus sorafenib; FGF401 PD markers</p>
    FGF19
    Hepatocellular cancer
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