Pleomorphic hyalinizing angiectatic tumor: FNA analysis of a rare entity and review of the literature
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Case Reports| February 15 2011 Cystic Fluid and Fine Needle Aspiration Cytopathology of Cystic Adult Granulosa Cell Tumor of the Ovary: A Case Report Subject Area: Pathology and Cell Biology Sevgiye Kaçar Özkara; Sevgiye Kaçar Özkara From the Department of Pathology, Faculty of Medicine, Kocaeli University, Gebze, Kocaeli, Turkey. Search for other works by this author on: This Site PubMed Google Scholar Gupse Turan Gupse Turan From the Department of Pathology, Faculty of Medicine, Kocaeli University, Gebze, Kocaeli, Turkey. Search for other works by this author on: This Site PubMed Google Scholar Acta Cytologica (2008) 52 (2): 247–250. https://doi.org/10.1159/000325492 Article history Published Online: February 15 2011 Content Tools Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation Sevgiye Kaçar Özkara, Gupse Turan; Cystic Fluid and Fine Needle Aspiration Cytopathology of Cystic Adult Granulosa Cell Tumor of the Ovary: A Case Report. Acta Cytologica 1 April 2008; 52 (2): 247–250. https://doi.org/10.1159/000325492 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsActa Cytologica Search Advanced Search Article PDF first page preview Close Modal This content is only available via PDF. 2008Copyright / Drug Dosage / DisclaimerCopyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. You do not currently have access to this content.
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INTRODUTION Primary penile sarcoma is an extremely rare condition. The incidence of penile sarcoma is described as 0.6 to 1 out of 100,000 patients in developed countries, and leiomyosarcoma is the predominant histological type. Given such a low incidence, treatment for this condition is very controversial. The authors could not find in the literature any other case of penile sarcoma with such histological findings (Pleomorphic undifferentiated sarcoma). […] Pleomorphic undifferentiated sarcoma of the penis
Undifferentiated Pleomorphic Sarcoma
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Cytopathology
Endoscopic Ultrasound
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Cytopathology
Fine needle biopsy
Aspiration biopsy
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The cytopathology of benign and malignant breast lesions is described and correlated with the histopathology. Problems in diagnosis and the advantages of fine-needle aspiration are discussed. The diagnostic accuracy is approximately 93% with this technique.
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Undifferentiated pleomorphic sarcoma not otherwise specified (NOS) is a malignant neoplasm of uncertain origin arising both in the soft tissue and the bone. The WHO classified this tumour in 2002 but controversy has plagued this entity due to limited availability of tissue for study. The aim of this study was to establish a reproducible xenograft model of primary human undifferentiated pleomorphic sarcoma NOS.Primary human sarcoma samples were divided into tumour fragments and transplanted subcutaneously in mice. Sarcoma xenografts were analysed histolomorphologically (light/electron-microscopy; immunohistochemistry).All tumours resulted in viable sarcoma NOS xenografts demonstrating similar histological patterns. In both the original tumours and the xenografts, tumour necrosis was found ranging from 15% to 25%. The background stroma of the xenografts was hyalinised like the primary sarcoma. Electron microscopical analyses showed good maintenance of ultrastructure.Implantation of intact tumor fragments yielded in a complete tumor take rate. The development of new cancer therapeutics requires animal models that closely resemble the human patient. This study provides ideal animal models for the research of pathogenesis and pathobiology of primary human undifferentiated pleomorphic sarcoma NOS.
Undifferentiated Pleomorphic Sarcoma
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Undifferentiated Pleomorphic Sarcoma
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Diagnosis of malignant lymphoma by fine-needle aspiration biopsy (FNAB) remains a topic of skepticism and controversy. Because of the limitations of pure morphology, subclassfication of non-Hodgkin malignant lymphoma (NHML) by FNAB often requires ancillary studies which impose a challenge not typically required of other FNAB diagnoses. Despite the dubiousness expressed by many, the evidence shows that a large percentage of NHML cases can be recognized and correctly classified using FNAB. Diagnostic accuracy is dependent on several factors including the type of NHML. The emergent WHO classification of lymphomas is one that appears to more readily accommodate the cytologic methods for NHML diagnosis. Diagn. Cytopathol. 2000;22:120–125. © 2000 Wiley-Liss, Inc.
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Malignant lymphoma
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Myxofibrosarcoma
Undifferentiated Pleomorphic Sarcoma
Histiocytic sarcoma
Bone Sarcoma
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Background: The thyroid gland is responsible for various functions, but it is susceptible to pathologies. The gold standard for preliminarily diagnosing thyroid abnormalities is fine-needle aspiration cytology (FNAC), although it has some limitations; thus, postoperative histopathological examination confirms the diagnosis. The aim of the present study was to compare preoperative FNAC results with postoperative histopathological examination. Methods: This study is a retrospective study based on FNAC and postoperative histopathology examination, which were compared and analyzed. Results: This study included 344 patients between 18 and 86 years old (mean age: 53.06 ± 13.89), comprising 274 females and 70 males (mean ages 52.72 ± 13.86 and 54.39 ± 14.05, respectively) with a 3.9:1 female-to-male ratio. Statistical significance between the FNAC and histopathology results was observed (p = 0.0000), and 86 (25.00%) patients were found to have been diagnosed incorrectly based on FNAC. The sensitivity of FNAC was 92.31%, and its specificity was 82.08%, with positive and negative predictive values of 68.57% and 96.08%, respectively. Conclusions: Due to many factors, FNAC may lead to over- or under-diagnosis, increasing the chances of complications associated with the selected treatment. However, we do not have any other more accurate tools; therefore, FNAC should still remain as the gold standard of preliminary examination.
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Cytopathology
Histopathological examination
Gold standard (test)
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