Childhood‐onset Takayasu arteritis presenting as pyoderma gangrenosum‐like vasculitic ulceration: Three case reports and a literature review
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ABSTRACT We report a small case series of childhood‐onset Takayasu arteritis (c‐TA) presenting as pyoderma gangrenosum (PG)‐like vasculitic ulceration. The cutaneous vasculitic ulcers in systemic vasculitis are rare and severe, sometimes leading to delayed diagnosis and treatment. We summarised the clinical features and highlighted the warning signs of c‐TA associated with PG‐like vasculitic ulceration.Keywords:
Takayasu Arteritis
Arteritis
Takayasu's arteritis
Systemic vasculitis
Takayasu Arteritis
Arteritis
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Takayasu's arteritis
Systemic vasculitis
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In part 1 of this article, clinical features and imaging findings of Takayasu arteritis (also known as aortitis syndrome) were described in detail. In part 2, treatment of Takayasu arteritis will be first described and discussed. This will be followed by description of clinical features and imaging findings of other systemic vasculitis. Comments on interventional radiology for systemic vasculitis will also be made.
Takayasu Arteritis
Arteritis
Aortitis
Systemic vasculitis
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Takayasu's arteritis (TA) is a chronic inflammatory arteritis, preferentially affecting the major arteries such as the aorta and its main branches. Its course may be biphasic, with an early systemic phase characterised by non-specific inflammatory features and a later stage with occlusive lesion of the affected vessels. We reported 3 patients with TA, who presented very varied symptoms. These cases emphasise the importance of ultrasound image, which can help to establish the diagnosis at very early stage of vasculitis and improve prognosis.
Takayasu Arteritis
Arteritis
Takayasu's arteritis
Systemic vasculitis
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ABSTRACT We report a small case series of childhood‐onset Takayasu arteritis (c‐TA) presenting as pyoderma gangrenosum (PG)‐like vasculitic ulceration. The cutaneous vasculitic ulcers in systemic vasculitis are rare and severe, sometimes leading to delayed diagnosis and treatment. We summarised the clinical features and highlighted the warning signs of c‐TA associated with PG‐like vasculitic ulceration.
Takayasu Arteritis
Arteritis
Takayasu's arteritis
Systemic vasculitis
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Pyoderma gangrenosum (PG) is a neutrophilic dermatosis characterized by destructive, necrotizing and noninfective ulceration of the skin mostly on lower extremities. PG is well known as a complication of Takayasu's arteritis in Japan. However, this association is not commonly observed in North American and European patients. We describe a case of PG that was associated with Takayasu's arteritis who was successfully treated with systemic cyclosporin. We have reviewed 35 well-documented PG cases with Takayasu's arteritis in comparison to 106 PG cases without Takayasu's arteritis. The results demonstrate that this association occurs predominantly in young females and that these cases exhibit more widespread PG lesions.
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Takayasu Arteritis
Takayasu's arteritis
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Takayasu’s arteritis presenting as acute myocardial infarction: case series and review of literature
This series describes three adolescent females who presented with chest pain and ventricular dysfunction related to acute coronary ischemia secondary to Takayasu's arteritis with varied courses of disease progression leading to a diverse range of therapies including cardiac transplantation. While Takayasu's arteritis is rare in childhood, it should be strongly considered in any adolescent female presenting with systemic inflammation and chest pain consistent with myocardial infarction. A high index of suspicion can lead to early detection and aggressive management of the underlying vasculitis reducing associated morbidity and mortality. The purpose of this report is to describe the challenges in the clinical diagnosis and management of Takayasu's arteritis with myocardial infarction. We also seek to enhance awareness about unique presentations of Takayasu's arteritis within the paediatric community.
Takayasu's arteritis
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Introduction: Takayasu Arteritis and Systemic Lupus Erythematosus affect the same age group and gender. Yet the former affects the large arteries, while the later affects the small blood vessels. Thus overlap of the two in the same patient is a rarity. We present the case of a young woman who presented with hemiple Case: gia and was rst diagnosed as a case of Takayasu Arteritis but on further evaluation found to have Systemic Lupus Erythematosus also along with antiphospholipid antibody positivity. We also search the literature and explore and discuss various aspects of the case. We conclude that this rare overla Conclusion: p may be increasingly reported as awareness about it increases among clinicians. Also noted is the higher number of such cases reported from Japan, which also has higher geographical prevalence of Behcet's disease.
Takayasu Arteritis
Arteritis
Systemic vasculitis
Takayasu's arteritis
Systemic lupus
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Takayasu's arteritis (TA) is a systemic vasculitis that affects mainly the aorta and its major branches. Despite being the third most frequent vasculitis in childhood, the occurrence of TA in the pediatric age group is scarce. We report three cases of TA in children, emphasizing signs and symptoms, angiographic alterations and therapeutics.
Takayasu Arteritis
Arteritis
Takayasu's arteritis
Systemic vasculitis
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