Stereotactic Radiosurgery and Stereotactic Radiotherapy for Brain Tumors
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Stereotactic radiosurgery (SRS) and fractionated stereotactic radiotherapy (FSRT) have become important treatment modalities for brain tumors.A technique that delivers a high dose of radiation, with effective use in patients with life-limiting diseases.Due to its specificity, the precision and direct visualization of the target during the delivery of the treatment is very important.The aim of this research article is to provide the safety and long-term efficacy of SRS and SRT.This research article, also, provides accuracy of the SRS treatment performed on linear accelerator and use of the trUpoint ARCH SRS system for patient imobilization.Introduction: Considering the tumor characteristics of the vestibular schwannoma (VS), physician and patient must decide among three major treatment options: radiotherapy (radiosurgery [RS] or stereotactic fractionated radiotherapy [SFR]), microsurgery, or observation. Based on the data of the literature and our own results, we will discuss the pro and con arguments for the use of RS and SFR in the management of VS.
Acoustic neuroma
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Introduction: Vestibular schwannoma (VS) is a benign tumor derived from Schwann cells typically in association with CN VIII. Common morbidities of these characteristically slow-growing lesions include hearing loss and facial nerve damage. Treatment options include observation, surgical resection, stereotactic radiosurgery (SRS), and stereotactic radiotherapy (SRT). In this study, we assess the outcomes of patients with VS treated with either SRS or SRT.
Acoustic neuroma
Vestibular Schwannomas
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Surgical resection
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Stereotactic radiosurgery (SRS) and hypofractionated stereotactic radiotherapy (HFSRT) have become important treatment modalities for brain metastases. While effective, there are still areas of extensive debate on its appropriate use in patients with life-limiting diseases. This review provides an overview of the indications and challenges of SRS and HFSRT in the management of brain metastases.
Limiting
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Stereotactic radiation therapy
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The advancement and trend of the measures, indications, outcome and complication prevention regarding stereotactic radiosurgery and stereotactic radiotherapy for cerebral arteriovenous malformations are discussed.
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”Oligometastasis” describes a limited number of metastases arising typically from solid tumors whose behavior suggests an “intermediate” malignant state since it may potentially have a more favorable prognosis. Historically, selected patients with oligometastases often underwent surgical resection since an ecdotal evidence suggested it could improve progression-free or overall survival. No prospective randomized trial evidence to date supports survival benefits from surgery. Short courses of highly focused, very high dose radiotherapy (stereotactic radiosurgery; stereotactic body radiotherapy) have emerged as a surgical surrogate to manage oligometastates. Forsolitary brain metastases, randomized study evidence supports stereotactic radiosurgery as part of their management because of overall survival benefits. Modeled after stereotactic radiosurgery, stereotactic body radiotherapy for extracranial metastases is becoming increasingly common given its efficacy and low toxicity, is an active area of clinical research, and is the subject of this review.
Surgical resection
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The treatment of resected brain metastasis has shifted away from the historical use of whole-brain radiotherapy (WBRT) toward adjuvant radiosurgery (stereotactic radiosurgery [SRS]) based on a recent prospective clinical trial demonstrating less cognitive decline with the use of SRS alone and equivalent survival as compared with WBRT. Whereas all level 1 evidence to date concerns single-fraction SRS for postoperative brain metastasis, there is emerging evidence that fractionated stereotactic radiotherapy (FSRT) may improve local control at the resected tumor bed. The lack of direct comparative data for SRS vs FSRT results in a diversity in clinical practice. In this article, Greenspoon and Roberge defend the use of SRS as the standard of care for resected brain metastasis, whereas Palmer and Brown argue for FSRT.
Surgical resection
Stereotactic surgery
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Stereotactic radiosurgery (SRS) and fractionated stereotactic radiotherapy (FSRT) have become important treatment modalities for brain tumors.A technique that delivers a high dose of radiation, with effective use in patients with life-limiting diseases.Due to its specificity, the precision and direct visualization of the target during the delivery of the treatment is very important.The aim of this research article is to provide the safety and long-term efficacy of SRS and SRT.This research article, also, provides accuracy of the SRS treatment performed on linear accelerator and use of the trUpoint ARCH SRS system for patient imobilization.
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