Diterpenoids from the roots of Euphorbia ebracteolata and their anti-tuberculosis effects
Zhenlong YuYun‐Long WeiXiangge TianQiulong YanQingsong YanXiaokui HuoChao WangCheng‐Peng SunBaojing ZhangXiaochi Ma
26
Citation
27
Reference
10
Related Paper
Citation Trend
Keywords:
Euphorbia
Abietane
IC50
Natural product
Abietane
Martinique
Cite
Citations (39)
Abietane
Cupressaceae
Cite
Citations (92)
Abietane
Cite
Citations (5)
Abietane
Cite
Citations (9)
Abietane
Salvia
Cite
Citations (33)
Abietane
Terpene
Cite
Citations (3)
Abietane
Terpene
Cite
Citations (20)
A new abietane diterpenoid, teuvisone (2), a pair of new dimeric abietane diterpenoid stereoisomers, biteuvisones A (3) and B (4), and three new sesquiterpenoid lactones, teuvislactones A–C (6, 7, and 10), were isolated from the whole plants of Teucrium viscidum, along with four known terpenoids (1, 5, 8, and 9). The structures of the new compounds were elucidated by spectroscopic analysis, and the absolute configurations of 5–10 were determined by electronic circular dichroism analysis. The isolated compounds were evaluated for their cytotoxic effects against five human cancer cell lines and for their α-glucosidase inhibitory effects.
Abietane
Absolute Configuration
Cancer cell lines
Teucrium
Cite
Citations (22)
A new abietane diterpenoid, tripterregeline A (1), together with six known diterpenoids (2–7), were isolated from the roots of Tripterygium regelii. The structure of 1 was elucidated by extensive spectroscopic methods and the known compounds were identified by comparison with data reported in the literature. All isolated compounds were evaluated for their cytotoxicities against five human cancer cell lines: HL-60, SMMC-7721, A-549, MCF-7 and SW480 in vitro. Compounds 1–7 showed significant inhibitory effects against various human cancer cell lines with IC50 values ranging from 0.58 to 21.06 μM.
Abietane
Tripterygium
Cancer cell lines
Tripterygium wilfordii
Leucas
Cite
Citations (8)